deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04447235

Early Treatment With Ivermectin and LosarTAN for Cancer Patients With COVID-19 Infection (TITAN)

Randomized, Doubled-blind Phase II Trial Evaluating the Use of Ivermectin Plus Losartan for Prophylaxis of Severe Events in Cancer Patients With Recent Diagnosis of COVID-19

Sponsor: Instituto do Cancer do Estado de São Paulo

Updated 8 times since 2020 Last updated: Aug 5, 2022 Started: Jul 23, 2020 Primary completion: Jun 30, 2022 Completion: Jun 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

futility analysis has demonstrated no difference between arms

Listed as NCT04447235, this PHASE2 trial focuses on COVID and Cancer and remains terminated or withdrawn. Sponsored by Instituto do Cancer do Estado de São Paulo, it has been updated 8 times since 2020, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Jul 2020 – ~Aug 2020 · 31 days · monthly snapshotNot Yet Recruiting~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshotRecruiting~Jan 2021 – ~Jul 2022 · 18 months · monthly snapshotRecruiting~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshotUnknown Status~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Sep 2022 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: Unknown StatusTerminated

  5. Jul 2022 — Sep 2022 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

Show 3 earlier versions
  1. Jan 2021 — Jul 2022 [monthly]

    Recruiting PHASE2

  2. Aug 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  3. Jul 2020 — Aug 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Instituto do Cancer do Estado de São Paulo
Data source: Instituto do Cancer do Estado de São Paulo

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations