deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT04454788

Extending the Time Window for Tenecteplase by Effective Reperfusion in Patients with Large Vessel Occlusion (ETERNAL-LVO)

Extending the Time Window for Tenecteplase by Effective Reperfusion of PeNumbrAL Tissue in Patients with Large Vessel Occlusion

Sponsor: Professor Mark Parsons

Updated 8 times since 2020 Last updated: Jan 13, 2025 Started: Aug 1, 2020 Primary completion: Jul 28, 2024 Completion: Jan 6, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Loss of equipoise in the 0-4.5h population which comprised the majority of ETERNAL-LVO trial recruitment due to publication of other trials demonstrating efficacy of tenecteplase vs alteplase in the 0-4.5h time window.

A PHASE3 clinical study on Ischemic Stroke, this trial is terminated or withdrawn. The trial is conducted by Professor Mark Parsons and has accumulated 8 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshotNot Yet Recruiting~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotRecruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Jul 2024 · 34 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshotRecruiting~Feb 2025 – ~Sep 2025 · 7 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE3

  2. Feb 2025 — Sep 2025 [monthly]

    Terminated PHASE3

    Status: RecruitingTerminated

  3. Sep 2024 — Feb 2025 [monthly]

    Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  5. Sep 2021 — Jul 2024 [monthly]

    Recruiting PHASE3

Show 3 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  2. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  3. Aug 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Professor Mark Parsons
  • University of Melbourne
Data source: University of Melbourne

For direct contact, visit the study record on ClinicalTrials.gov .