deltatrials
Completed PHASE2 INTERVENTIONAL 5-arm NCT04457310

A Translational and Neurocomputational Evaluation of a Dopamine Receptor 1 Partial Agonist for Schizophrenia

Sponsor: Cerevel Therapeutics, LLC

Updated 14 times since 2020 Last updated: Sep 27, 2025 Started: Mar 2, 2021 Primary completion: Mar 22, 2024 Completion: Mar 22, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE2 trial investigates Early Course Schizophrenia Spectrum Disorder and is currently completed. Cerevel Therapeutics, LLC leads this study, which shows 14 recorded versions since 2021 — indicating substantial longitudinal coverage. This study adds to the longitudinal dataset for psychiatric treatment development.

Status Flow

~Aug 2020 – ~Dec 2020 · 4 months · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshot~Sep 2022 – ~May 2023 · 8 months · monthly snapshot~May 2023 – ~Jul 2023 · 2 months · monthly snapshot~Jul 2023 – ~Jun 2024 · 11 months · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2025 · 5 months · monthly snapshot~Feb 2025 – ~Apr 2025 · 59 days · monthly snapshot~Apr 2025 – ~Nov 2025 · 7 months · monthly snapshot~Nov 2025 – present · 8 months · monthly snapshot

Change History

14 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE2

    Phase: PHASE1/PHASE2PHASE2

  2. Apr 2025 — Nov 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Feb 2025 — Apr 2025 [monthly]

    Completed PHASE1/PHASE2

    Status: Active Not RecruitingCompleted

  4. Sep 2024 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

Show 9 earlier versions
  1. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  2. Jul 2023 — Jun 2024 [monthly]

    Recruiting PHASE1_PHASE2

  3. May 2023 — Jul 2023 [monthly]

    Recruiting PHASE1_PHASE2

  4. Sep 2022 — May 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Sep 2021 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Jan 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  8. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  9. Aug 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Cerevel Therapeutics, LLC
  • Columbia University
  • National Institute of Mental Health (NIMH)
  • State University of New York Stony Brook
  • University of Pennsylvania
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .