deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT04466540

Randomized Placebo-controlled Trial of Hydroxychloroquine in Outpatient Cases With Coronavirus Disease 2019 (COVID-19) (COALITION-V)

Pragmatic, Double-blind, Placebo-controlled Randomized Clinical Trial, Evaluating Hydroxychloroquine for Prevention of Hospitalization and Respiratory Complications in Non-hospitalized Patients With Confirmed or Probable COVID-19

Sponsor: Brazilian Research In Intensive Care Network

Conditions COVID-19
Updated 8 times since 2020 Last updated: Mar 4, 2022 Started: May 12, 2020 Primary completion: Jul 28, 2021 Completion: Sep 28, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04466540, this PHASE4 trial focuses on COVID-19 and remains completed. Sponsored by Brazilian Research In Intensive Care Network, it has been updated 8 times since 2020, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Aug 2020 – ~Dec 2020 · 4 months · monthly snapshotRecruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Sep 2021 · 8 months · monthly snapshotRecruiting~Sep 2021 – ~Apr 2022 · 7 months · monthly snapshotActive Not Recruiting~Apr 2022 – ~Jul 2024 · 27 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Apr 2022 — Jul 2024 [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  5. Sep 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

Show 3 earlier versions
  1. Jan 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE4

  3. Aug 2020 — Dec 2020 [monthly]

    Recruiting PHASE4

    First recorded

May 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Brazilian Research In Intensive Care Network
  • EMS S/A
  • Hospital Alemão Oswaldo Cruz
  • Hospital Israelita Albert Einstein
  • Hospital Moinhos de Vento
  • Hospital Sirio-Libanes
  • Hospital do Coracao
Data source: Hospital Alemão Oswaldo Cruz

For direct contact, visit the study record on ClinicalTrials.gov .