deltatrials
Active Not Recruiting PHASE2 INTERVENTIONAL 2-arm NCT04469959

Dopaminergic Dysfunction in Late-Life Depression (D3)

Sponsor: Emory University

Interventions L-Dopa Placebo
Updated 14 times since 2020 Last updated: Feb 4, 2026 Started: Feb 15, 2021 Primary completion: Apr 30, 2026 Completion: Jul 30, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Cognitive Decline and Depressive Disorder, Treatment-Resistant, this trial is ongoing. The trial is conducted by Emory University and has accumulated 14 data snapshots since 2021. Psychiatric clinical trials are essential for establishing evidence-based treatment standards.

Status Flow

~Aug 2020 – ~Nov 2020 · 3 months · monthly snapshot~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Mar 2022 · 12 months · monthly snapshot~Mar 2022 – ~Apr 2023 · 13 months · monthly snapshot~Apr 2023 – ~Mar 2024 · 11 months · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Feb 2026 · 5 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

14 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Sep 2025 — Feb 2026 [monthly]

    Recruiting PHASE2

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE2

  5. Aug 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

Show 9 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE2

  2. Apr 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  3. Mar 2024 — Apr 2024 [monthly]

    Recruiting PHASE2

  4. Apr 2023 — Mar 2024 [monthly]

    Recruiting PHASE2

  5. Mar 2022 — Apr 2023 [monthly]

    Recruiting PHASE2

  6. Mar 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  8. Nov 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

  9. Aug 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Emory University
  • Rutgers University
  • University of North Carolina, Chapel Hill
  • University of Pittsburgh
  • University of Pittsburgh Medical Center
  • Vanderbilt University Medical Center
Data source: Vanderbilt University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .