deltatrials
Recruiting PHASE1 INTERVENTIONAL 2-arm NCT04470024

Phase Ib Trial of Multivalent Autophagosome Vaccine With or Without GITR Agonist, With Anti-PD-1 Immunotherapy in HNSCC

A Phase Ib Study of Multivalent Autophagosome Vaccine, With or Without GITR Agonist, With Sequenced Checkpoint Inhibition (Anti-PD-1) - Immunotherapy Trio in Recurrent or Metastatic Head and Neck Squamous Cell Carcinoma (HNSCC)

Sponsor: Providence Health & Services

Conditions Cancer of the Head and Neck
Interventions DPV-001 INCAGN01876 INCMGA00012
Updated 8 times since 2020 Last updated: Jul 9, 2025 Started: Aug 5, 2021 Primary completion: Dec 31, 2025 Completion: Dec 31, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Cancer of the Head and Neck and is currently actively recruiting participants. Providence Health & Services leads this study, which shows 8 recorded versions since 2021 — indicating limited longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Aug 2020 – ~Jan 2021 · 5 months · monthly snapshot~Jan 2021 – ~Oct 2021 · 9 months · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Sep 2022 · 11 months · monthly snapshotRecruiting~Sep 2022 – ~Sep 2023 · 12 months · monthly snapshotRecruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Aug 2025 · 11 months · monthly snapshotRecruiting~Aug 2025 – present · 12 months · monthly snapshotRecruiting

Change History

8 versions recorded

  1. Aug 2025 — Present [monthly]

    Recruiting PHASE1

  2. Sep 2024 — Aug 2025 [monthly]

    Recruiting PHASE1

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

    Status: Active Not Recruiting → Recruiting

  4. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  5. Sep 2022 — Sep 2023 [monthly]

    Recruiting PHASE1

▶ Show 3 earlier versions

  1. Oct 2021 — Sep 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  2. Jan 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE1

  3. Aug 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Providence Health & Services
Data source: Providence Health & Services

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations