deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04479436

A Study to Evaluate U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer

A Multi-Center, Open-Label, Phase 2 Study to Evaluate Safety and Efficacy of U3-1402 in Subjects With Advanced or Metastatic Colorectal Cancer (CRC)

Sponsor: Daiichi Sankyo

Updated 13 times since 2020 Last updated: May 2, 2025 Started: Sep 14, 2020 Primary completion: Feb 3, 2022 Completion: Feb 3, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Study was terminated early given the Interim Analysis for Part 1 (signal finding) did not meet pre-specified criteria and will not proceed to Part 2. Sponsor will proceed closing the study.

A PHASE2 clinical study on Metastatic Colorectal Cancer, this trial is terminated or withdrawn. The trial is conducted by Daiichi Sankyo and has accumulated 13 data snapshots since 2020. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Aug 2020 – ~Oct 2020 · 2 months · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Dec 2021 · 9 months · monthly snapshot~Dec 2021 – ~May 2022 · 5 months · monthly snapshot~May 2022 – ~Feb 2023 · 9 months · monthly snapshot~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshot~Jun 2025 – ~Sep 2025 · 3 months · monthly snapshot~Sep 2025 – present · 12 months · monthly snapshot

Change History

13 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Jun 2025 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Sep 2024 — Jun 2025 [monthly]

    Terminated PHASE2

  4. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  5. Mar 2024 — Jul 2024 [monthly]

    Terminated PHASE2

Show 8 earlier versions
  1. Feb 2023 — Mar 2024 [monthly]

    Terminated PHASE2

  2. May 2022 — Feb 2023 [monthly]

    Terminated PHASE2

  3. Dec 2021 — May 2022 [monthly]

    Terminated PHASE2

    Status: RecruitingTerminated

  4. Mar 2021 — Dec 2021 [monthly]

    Recruiting PHASE2

  5. Feb 2021 — Mar 2021 [monthly]

    Recruiting PHASE2

  6. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  7. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  8. Aug 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Daiichi Sankyo
Data source: Daiichi Sankyo

For direct contact, visit the study record on ClinicalTrials.gov .