deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04483479

Orally Administered ENT-01 for Parkinson's Disease-Related Constipation Follow-on Safety Roll-over Study (Rollover) (Rollover)

A Multicenter, Non-Randomized, Open-Label Study to Evaluate the Safety and Efficacy of Orally Administered ENT-01 in Improving Constipation and Neurologic Symptoms in Patients With Parkinson's Disease and Constipation Over a 14-week Period

Sponsor: Enterin Inc.

Updated 12 times since 2020 Last updated: Feb 20, 2024 Started: Jul 30, 2020 Primary completion: Feb 17, 2022 Completion: Feb 17, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Poor recruitment/retention due to the pandemic. Data was not analyzed due to early termination.

This PHASE2 trial investigates Constipation and Parkinson Disease and is currently terminated or withdrawn. Enterin Inc. leads this study, which shows 12 recorded versions since 2020 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Aug 2020 – ~Sep 2020 · 31 days · monthly snapshotNot Yet Recruiting~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshotRecruiting~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshotRecruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotRecruiting~Feb 2021 – ~Apr 2022 · 14 months · monthly snapshotRecruiting~Apr 2022 – ~Jul 2023 · 15 months · monthly snapshotCompleted~Jul 2023 – ~Apr 2024 · 9 months · monthly snapshotTerminated~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotTerminated~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  4. Apr 2024 — Jul 2024 [monthly]

    Terminated PHASE2

  5. Jul 2023 — Apr 2024 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

Show 7 earlier versions
  1. Apr 2022 — Jul 2023 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

  2. Feb 2021 — Apr 2022 [monthly]

    Recruiting PHASE2

  3. Jan 2021 — Feb 2021 [monthly]

    Recruiting PHASE2

  4. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

  5. Oct 2020 — Nov 2020 [monthly]

    Recruiting PHASE2

  6. Sep 2020 — Oct 2020 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Aug 2020 — Sep 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Jul 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Enterin Inc.
Data source: Enterin Inc.

For direct contact, visit the study record on ClinicalTrials.gov .