A Study to Evaluate the Safety and Efficacy of AZD5718 in Participants With Proteinuric Chronic Kidney Disease
A Phase 2b Randomised, Double-Blind, Placebo-Controlled, Multi-Centre, Dose-Ranging Study of AZD5718 in Participants With Proteinuric Chronic Kidney Disease
Sponsor: AstraZeneca
Terminated
The Sponsor decided to terminate the study early due to lack of efficacy. There were no safety concerns related to the study.
Other terminated trials from AstraZeneca
Other Chronic Kidney Disease trials with similar outcome
This PHASE2 trial investigates Chronic Kidney Disease and is currently terminated or withdrawn. AstraZeneca leads this study, which shows 25 recorded versions since 2020 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.
Status Flow
Change History
25 versions recorded-
Sep 2025 — Present [monthly]
Terminated PHASE2
-
Jan 2025 — Sep 2025 [monthly]
Terminated PHASE2
-
Sep 2024 — Jan 2025 [monthly]
Terminated PHASE2
-
Jul 2024 — Sep 2024 [monthly]
Terminated PHASE2
-
Jan 2024 — Jul 2024 [monthly]
Terminated PHASE2
Status: Completed → Terminated
▶ Show 20 earlier versions
-
Nov 2022 — Jan 2024 [monthly]
Completed PHASE2
Status: Active Not Recruiting → Completed
-
Sep 2022 — Nov 2022 [monthly]
Active Not Recruiting PHASE2
Status: Recruiting → Active Not Recruiting
-
Jun 2022 — Sep 2022 [monthly]
Recruiting PHASE2
-
May 2022 — Jun 2022 [monthly]
Recruiting PHASE2
-
Apr 2022 — May 2022 [monthly]
Recruiting PHASE2
-
Mar 2022 — Apr 2022 [monthly]
Recruiting PHASE2
-
Feb 2022 — Mar 2022 [monthly]
Recruiting PHASE2
-
Jan 2022 — Feb 2022 [monthly]
Recruiting PHASE2
-
Dec 2021 — Jan 2022 [monthly]
Recruiting PHASE2
-
Nov 2021 — Dec 2021 [monthly]
Recruiting PHASE2
-
Oct 2021 — Nov 2021 [monthly]
Recruiting PHASE2
-
Sep 2021 — Oct 2021 [monthly]
Recruiting PHASE2
-
Jun 2021 — Sep 2021 [monthly]
Recruiting PHASE2
-
May 2021 — Jun 2021 [monthly]
Recruiting PHASE2
-
Apr 2021 — May 2021 [monthly]
Recruiting PHASE2
-
Feb 2021 — Apr 2021 [monthly]
Recruiting PHASE2
-
Jan 2021 — Feb 2021 [monthly]
Recruiting PHASE2
-
Nov 2020 — Jan 2021 [monthly]
Recruiting PHASE2
Status: Not Yet Recruiting → Recruiting
-
Sep 2020 — Nov 2020 [monthly]
Not Yet Recruiting PHASE2
-
Aug 2020 — Sep 2020 [monthly]
Not Yet Recruiting PHASE2
First recorded
Eligibility Summary
No eligibility information available.
Contact Information
- AstraZeneca
- Emerald Clinical Inc.
- Parexel
For direct contact, visit the study record on ClinicalTrials.gov .
Study Locations
Afula, Israel , Ageo, Japan , Asahikawa-shi, Japan , Aschaffenburg, Germany , Ashdod, Israel , Ashkelon, Israel , Austin, United States , Bahía Blanca, Argentina , Balatonfüred, Hungary , Belém, Brazil and 78 more locations