deltatrials
Completed PHASE2 INTERVENTIONAL 2-arm NCT04498169

A Phase 2 Study Evaluating the Safety and Efficacy of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy (Fuchs)

A Randomized, Open-Label, Parallel-Group Study to Evaluate the Safety and Efficacy of Two Dosing Regimens of Netarsudil Ophthalmic Solution in Patients With Corneal Edema Due to Fuchs Corneal Dystrophy

Sponsor: Aerie Pharmaceuticals

Conditions Corneal Edema
Updated 9 times since 2020 Last updated: Aug 31, 2022 Started: Sep 17, 2020 Primary completion: Aug 11, 2021 Completion: Aug 11, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04498169, this PHASE2 trial focuses on Corneal Edema and remains completed. Sponsored by Aerie Pharmaceuticals, it has been updated 9 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Sep 2020 – ~Nov 2020 · 2 months · monthly snapshotNot Yet Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotRecruiting~Jan 2021 – ~Jun 2021 · 5 months · monthly snapshotRecruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotRecruiting~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshotCompleted~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotCompleted~Sep 2025 – present · 10 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE2

  2. Sep 2024 — Sep 2025 [monthly]

    Completed PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE2

  4. Sep 2022 — Jul 2024 [monthly]

    Completed PHASE2

  5. Sep 2021 — Sep 2022 [monthly]

    Completed PHASE2

    Status: RecruitingCompleted

Show 4 earlier versions
  1. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  2. Jan 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  3. Nov 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  4. Sep 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Aerie Pharmaceuticals
Data source: Aerie Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .