deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 5-arm NCT04505566

INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy Study (INSPIRE)

INflammatory MediatorS in the PathophysIology of Diabetic REtinopathy (INSPIRE) Study

Sponsor: Allergan

Conditions Diabetic Retinopathy
Interventions Aqueous PGE2 and inflammatory cytokines measurements Ketorolac 0.45% ophthalmic solution Placebo - Preservative-free artificial tears
Updated 12 times since 2020 Last updated: Jan 19, 2026 Started: Nov 9, 2020 Primary completion: May 31, 2026 Completion: May 31, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Diabetic Retinopathy, this trial is ongoing. The trial is conducted by Allergan and has accumulated 12 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshotNot Yet Recruiting~Nov 2020 – ~Jan 2021 · 2 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2022 · 14 months · monthly snapshotRecruiting~Mar 2022 – ~Mar 2023 · 12 months · monthly snapshotRecruiting~Mar 2023 – ~Apr 2024 · 13 months · monthly snapshotRecruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotActive Not Recruiting~Oct 2024 – ~Oct 2025 · 12 months · monthly snapshotActive Not Recruiting~Oct 2025 – ~Feb 2026 · 4 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 6 months · monthly snapshotActive Not Recruiting

Change History

12 versions recorded

  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Oct 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Oct 2024 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

▶ Show 7 earlier versions

  1. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  2. Mar 2023 — Apr 2024 [monthly]

    Recruiting PHASE1

  3. Mar 2022 — Mar 2023 [monthly]

    Recruiting PHASE1

  4. Jan 2021 — Mar 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  5. Nov 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

  6. Oct 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE1

  7. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Allergan
  • National Eye Institute (NEI)
  • Stephen J. Kim, MD
Data source: Vanderbilt University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations