deltatrials
Terminated PHASE2 INTERVENTIONAL 3-arm NCT04511130

Efficacy of MT-401 in Patients With AML Following Stem Cell Transplant (ARTEMIS)

A Phase 2 Study of Donor-Derived Multi-Tumor-Associated Antigen Specific T Cells (MT-401) Administered to Patients With Acute Myeloid Leukemia (AML) Following Hematopoietic Stem Cell Transplantation

Sponsor: Marker Therapeutics, Inc.

Interventions MT-401
Updated 18 times since 2020 Last updated: Oct 28, 2025 Started: Oct 14, 2020 Primary completion: Mar 1, 2024 Completion: Mar 1, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Despite a plan to enroll \~195-210 participants, the ARTEMIS study was closed due to the long vein-to-vein manufacturing timeline of MT-401 after 38 participants received the autologous MT-401.

Other terminated trials from Marker Therapeutics, Inc.

More terminations from Marker Therapeutics, Inc.

This PHASE2 trial investigates Acute Myeloid Leukemia and Stem Cell Transplantation and is currently terminated or withdrawn. Marker Therapeutics, Inc. leads this study, which shows 18 recorded versions since 2020 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2020 – ~Oct 2020 · 30 days · monthly snapshot~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshot~Jan 2021 – ~May 2021 · 4 months · monthly snapshot~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Apr 2022 · 5 months · monthly snapshot~Apr 2022 – ~Jul 2022 · 3 months · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Dec 2022 · 3 months · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshot~Apr 2023 – ~Apr 2024 · 12 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshot~Dec 2024 – ~Sep 2025 · 9 months · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 10 months · monthly snapshot

Change History

18 versions recorded
  1. Nov 2025 — Present [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  2. Sep 2025 — Nov 2025 [monthly]

    Completed PHASE2

  3. Dec 2024 — Sep 2025 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  4. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2

Show 13 earlier versions
  1. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

  2. Apr 2023 — Apr 2024 [monthly]

    Recruiting PHASE2

  3. Jan 2023 — Apr 2023 [monthly]

    Recruiting PHASE2

  4. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE2

  5. Sep 2022 — Dec 2022 [monthly]

    Recruiting PHASE2

  6. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE2

  7. Apr 2022 — Jul 2022 [monthly]

    Recruiting PHASE2

  8. Nov 2021 — Apr 2022 [monthly]

    Recruiting PHASE2

  9. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE2

  10. May 2021 — Sep 2021 [monthly]

    Recruiting PHASE2

  11. Jan 2021 — May 2021 [monthly]

    Recruiting PHASE2

  12. Oct 2020 — Jan 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  13. Sep 2020 — Oct 2020 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Marker Therapeutics, Inc.
Data source: Marker Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .