deltatrials
Completed NA INTERVENTIONAL 3-arm NCT04528134

Orthodontic Varnish Microbiology Study

The Effect of Light-cured Fluoride Varnish to Remineralize Post-orthodontic White Spot Lesions and Change the Oral Microbiome: a Double-blind, Split-mouth Randomized Clinical Trial

Sponsor: University of California, Los Angeles

Updated 12 times since 2020 Last updated: Aug 5, 2025 Started: Feb 7, 2022 Primary completion: Jul 1, 2025 Completion: Jul 1, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Dental Caries and Dental Plaque and is currently completed. University of California, Los Angeles leads this study, which shows 12 recorded versions since 2022 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2020 – ~Dec 2020 · 3 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotNot Yet Recruiting~May 2021 – ~Oct 2021 · 5 months · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Feb 2022 · 4 months · monthly snapshotNot Yet Recruiting~Feb 2022 – ~Jun 2023 · 16 months · monthly snapshotRecruiting~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshotRecruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotRecruiting~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotRecruiting~Sep 2025 – present · 12 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed NA

    Status: RecruitingCompleted

  2. Sep 2024 — Sep 2025 [monthly]

    Recruiting NA

  3. Aug 2024 — Sep 2024 [monthly]

    Recruiting NA

  4. Jul 2024 — Aug 2024 [monthly]

    Recruiting NA

  5. Jul 2023 — Jul 2024 [monthly]

    Recruiting NA

Show 7 earlier versions
  1. Jun 2023 — Jul 2023 [monthly]

    Recruiting NA

  2. Feb 2022 — Jun 2023 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  3. Oct 2021 — Feb 2022 [monthly]

    Not Yet Recruiting NA

  4. May 2021 — Oct 2021 [monthly]

    Not Yet Recruiting NA

  5. Jan 2021 — May 2021 [monthly]

    Not Yet Recruiting NA

  6. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting NA

  7. Sep 2020 — Dec 2020 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University of California, Los Angeles
Data source: University of California, Los Angeles

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations