deltatrials
Terminated PHASE3 INTERVENTIONAL 2-arm NCT04552899

A Study to Evaluate the Efficacy and Safety of Recombinant Human Pentraxin-2 (rhPTX-2; PRM-151) in Participants With Idiopathic Pulmonary Fibrosis (STARSCAPE)

A Phase III Randomized, Double-blind, Placebo Controlled Trial to Evaluate the Efficacy and Safety of PRM-151 in Patients With Idiopathic Pulmonary Fibrosis

Sponsor: Hoffmann-La Roche

Updated 35 times since 2020 Last updated: Mar 21, 2024 Started: Mar 19, 2021 Primary completion: Feb 10, 2023 Completion: Feb 10, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

The study was terminated by Sponsor as the futility analysis outcome indicated that the study was unlikely to meet the predefined primary objective of the study. No new safety concerns were identified.

This PHASE3 trial investigates Idiopathic Pulmonary Fibrosis and is currently terminated or withdrawn. Hoffmann-La Roche leads this study, which shows 35 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Oct 2020 – ~Nov 2020 · 31 days · monthly snapshot~Nov 2020 – ~Dec 2020 · 30 days · monthly snapshot~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshot~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~May 2021 · 30 days · monthly snapshot~May 2021 – ~Jun 2021 · 31 days · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~May 2024 · 11 months · monthly snapshot~May 2024 – ~Jul 2024 · 2 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Dec 2025 · 2 months · monthly snapshot~Dec 2025 – ~Mar 2026 · 3 months · monthly snapshot~Mar 2026 – present · 5 months · monthly snapshot

Change History

35 versions recorded
  1. Mar 2026 — Present [monthly]

    Terminated PHASE3

  2. Dec 2025 — Mar 2026 [monthly]

    Terminated PHASE3

  3. Oct 2025 — Dec 2025 [monthly]

    Terminated PHASE3

  4. Sep 2025 — Oct 2025 [monthly]

    Terminated PHASE3

  5. Sep 2024 — Sep 2025 [monthly]

    Terminated PHASE3

Show 30 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE3

  2. May 2024 — Jul 2024 [monthly]

    Terminated PHASE3

    Status: CompletedTerminated

  3. Jun 2023 — May 2024 [monthly]

    Completed PHASE3

  4. May 2023 — Jun 2023 [monthly]

    Completed PHASE3

  5. Apr 2023 — May 2023 [monthly]

    Completed PHASE3

    Status: Active Not RecruitingCompleted

  6. Mar 2023 — Apr 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  7. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE3

    Status: Active Not RecruitingRecruiting

  8. Jan 2023 — Feb 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  9. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  10. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE3

  11. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE3

  12. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE3

  13. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE3

  14. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE3

  15. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE3

  16. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE3

  17. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE3

  18. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE3

  19. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE3

  20. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE3

  21. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE3

  22. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE3

  23. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE3

  24. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE3

  25. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE3

  26. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  27. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE3

  28. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

  29. Nov 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE3

  30. Oct 2020 — Nov 2020 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Hoffmann-La Roche
Data source: Hoffmann-La Roche

For direct contact, visit the study record on ClinicalTrials.gov .