deltatrials
Completed PHASE1 INTERVENTIONAL 2-arm NCT04555486

Study to Evaluate Safety, Tolerability, PK and PD of DCR-PHXC in PH Type 3 Patients (PHYOX4)

A Phase 1 Placebo-Controlled, Double-Blind, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of a Single Dose of DCR-PHXC in Patients With Primary Hyperoxaluria Type 3

Sponsor: Dicerna Pharmaceuticals, Inc., a Novo Nordisk company

Updated 10 times since 2020 Last updated: Sep 11, 2024 Started: Sep 14, 2020 Primary completion: Sep 7, 2021 Completion: Sep 7, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Primary Hyperoxaluria Type 3, this trial is completed. The trial is conducted by Dicerna Pharmaceuticals, Inc., a Novo Nordisk company and has accumulated 10 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

~Oct 2020 – ~Jan 2021 · 3 months · monthly snapshotNot Yet Recruiting~Jan 2021 – ~May 2021 · 4 months · monthly snapshotNot Yet Recruiting~May 2021 – ~Sep 2021 · 4 months · monthly snapshotEnrolling By Invitation~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotActive Not Recruiting~Oct 2021 – ~Jun 2023 · 20 months · monthly snapshotCompleted~Jun 2023 – ~Jul 2024 · 13 months · monthly snapshotCompleted~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotCompleted~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotCompleted~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotCompleted~Oct 2024 – present · 21 months · monthly snapshotCompleted

Change History

10 versions recorded
  1. Oct 2024 — Present [monthly]

    Completed PHASE1

  2. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE1

  3. Aug 2024 — Sep 2024 [monthly]

    Completed PHASE1

  4. Jul 2024 — Aug 2024 [monthly]

    Completed PHASE1

  5. Jun 2023 — Jul 2024 [monthly]

    Completed PHASE1

Show 5 earlier versions
  1. Oct 2021 — Jun 2023 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

  2. Sep 2021 — Oct 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: Enrolling By InvitationActive Not Recruiting

  3. May 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE1

    Status: Not Yet RecruitingEnrolling By Invitation

  4. Jan 2021 — May 2021 [monthly]

    Not Yet Recruiting PHASE1

  5. Oct 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Sep 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Dicerna Pharmaceuticals, Inc., a Novo Nordisk company
Data source: Novo Nordisk A/S

For direct contact, visit the study record on ClinicalTrials.gov .