deltatrials
Completed PHASE1/PHASE2 INTERVENTIONAL 4-arm NCT04565756

A Study to Evaluate the Safety and Tolerability of EXN407

A Randomised, Double-Masked Vehicle-Controlled, Multiple Dose, Dose Escalation Study To Evaluate The Safety and Tolerability of EXN407 in Subjects With Centre Involved Diabetic Macular Oedema Secondary to Diabetes Mellitus

Sponsor: Exonate Limited

Interventions EXN407
Updated 12 times since 2020 Last updated: Apr 23, 2025 Started: Nov 5, 2020 Primary completion: Oct 25, 2022 Completion: Nov 29, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04565756, this PHASE1/PHASE2 trial focuses on Diabetic Macular Edema and remains completed. Sponsored by Exonate Limited, it has been updated 12 times since 2020, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Oct 2020 – ~Dec 2020 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotRecruiting~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshotRecruiting~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshotRecruiting~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshotRecruiting~Feb 2022 – ~Sep 2022 · 7 months · monthly snapshotRecruiting~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshotActive Not Recruiting~Feb 2023 – ~Jul 2024 · 17 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Jun 2025 · 9 months · monthly snapshotCompleted~Jun 2025 – present · 15 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Jun 2025 — Present [monthly]

    Completed PHASE1/PHASE2

  2. Sep 2024 — Jun 2025 [monthly]

    Completed PHASE1/PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  4. Feb 2023 — Jul 2024 [monthly]

    Completed PHASE1_PHASE2

    Status: Active Not RecruitingCompleted

  5. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

Show 7 earlier versions
  1. Feb 2022 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  2. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE1_PHASE2

  3. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE1_PHASE2

  4. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jan 2021 — Mar 2021 [monthly]

    Recruiting PHASE1_PHASE2

  6. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Oct 2020 — Dec 2020 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Exonate Limited
  • Novotech (Australia) Pty Limited
Data source: Exonate Limited

For direct contact, visit the study record on ClinicalTrials.gov .