Recruiting PHASE2 INTERVENTIONAL 2-arm NCT04576793

Longitudinal Imaging of Microglial Activation in Different Clinical Variants of Alzheimer's Disease (ADVISe)

Sponsor: National Institute on Aging (NIA)

Interventions 11C-ER176 18F-Florbetaben 18F-MK6240 Lumbar Puncture

Updated 8 times since 2020 Last updated: Jun 30, 2025 Started: Nov 17, 2020 Primary completion: May 31, 2026 Completion: May 31, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04576793, this PHASE2 trial focuses on Alzheimer Disease and remains actively recruiting participants. Sponsored by National Institute on Aging (NIA), it has been updated 8 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

8 versions recorded

Aug 2025 — Present [monthly]

Recruiting PHASE2
Sep 2024 — Aug 2025 [monthly]

Recruiting PHASE2
Jul 2024 — Sep 2024 [monthly]

Recruiting PHASE2
Sep 2022 — Jul 2024 [monthly]

Recruiting PHASE2
Sep 2021 — Sep 2022 [monthly]

Recruiting PHASE2

▶ Show 3 earlier versions

Apr 2021 — Sep 2021 [monthly]

Recruiting PHASE2
Jan 2021 — Apr 2021 [monthly]

Recruiting PHASE2
Nov 2020 — Jan 2021 [monthly]

Recruiting PHASE2

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institute on Aging (NIA)
Patrick Lao

Data source: Columbia University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• New York, United States