Completed NA INTERVENTIONAL 2-arm NCT04630626

Post-Approval Study Protocol for the Simplify Cervical Artificial Disc

Extended Follow-up of Investigational Device Exemption (IDE) Subjects Treated With the Simplify Cervical Artificial Disc

Sponsor: NuVasive

Conditions Cervical Degenerative Disc Disorder

Interventions ACDF Simplify Disc

Updated 10 times since 2020 Last updated: Dec 16, 2025 Started: Jan 1, 2021 Primary completion: Apr 23, 2023 Completion: Apr 23, 2023

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Cervical Degenerative Disc Disorder and is currently completed. NuVasive leads this study, which shows 10 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

Change History

10 versions recorded

Feb 2026 — Present [monthly]

Completed NA
Sep 2025 — Feb 2026 [monthly]

Completed NA
Dec 2024 — Sep 2025 [monthly]

Completed NA
Sep 2024 — Dec 2024 [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA

▶ Show 5 earlier versions

Jun 2024 — Jul 2024 [monthly]

Completed NA

Status: Active Not Recruiting → Completed · Phase: None → NA
Nov 2022 — Jun 2024 [monthly]

Active Not Recruiting
Apr 2021 — Nov 2022 [monthly]

Active Not Recruiting

Status: Not Yet Recruiting → Active Not Recruiting
Jan 2021 — Apr 2021 [monthly]

Not Yet Recruiting
Dec 2020 — Jan 2021 [monthly]

Not Yet Recruiting

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

NuVasive

Data source: Globus Medical Inc

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Addison, United States , Carmel, United States , Charlotte, United States , Egg Harbor, United States , Evanston, United States , Lockport, United States , Orange, United States , Paducah, United States , Plano, United States , Reston, United States and 5 more locations