deltatrials
Completed PHASE2 INTERVENTIONAL 12-arm NCT04634071

Tobacco Treatment Optimization and Preferences During Concurrent Cancer Treatment (TTOP)

Sponsor: Joseph Valentino, MD

Conditions Cancer, Treatment-Related Smoking Cessation
Interventions Bupropion High-intensity counseling Long-acting nicotine replacement therapy Low-intensity counseling Nicotine Replacement Products No nicotine replacement therapy Varenicline
Updated 11 times since 2020 Last updated: Jan 29, 2026 Started: Jan 12, 2021 Primary completion: Jan 2, 2026 Completion: Jan 2, 2026
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE2 clinical study on Cancer, Treatment-Related and Smoking Cessation, this trial is completed. The trial is conducted by Joseph Valentino, MD and has accumulated 11 data snapshots since 2021. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2021 – ~Mar 2022 · 12 months · monthly snapshotRecruiting~Mar 2022 – ~Feb 2023 · 11 months · monthly snapshotRecruiting~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshotRecruiting~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~Aug 2025 · 10 months · monthly snapshotRecruiting~Aug 2025 – ~Feb 2026 · 6 months · monthly snapshotActive Not Recruiting~Feb 2026 – present · 5 months · monthly snapshotCompleted

Change History

11 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed PHASE2

    Status: Active Not Recruiting → Completed

  2. Aug 2025 — Feb 2026 [monthly]

    Active Not Recruiting PHASE2

    Status: Recruiting → Active Not Recruiting

  3. Oct 2024 — Aug 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

▶ Show 6 earlier versions

  1. Mar 2024 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Feb 2023 — Mar 2024 [monthly]

    Recruiting PHASE2

  3. Mar 2022 — Feb 2023 [monthly]

    Recruiting PHASE2

  4. Mar 2021 — Mar 2022 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  5. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

  6. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Joseph Valentino, MD
Data source: University of Kentucky

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations