deltatrials
Completed PHASE3 INTERVENTIONAL 2-arm NCT04643639

Assessing the Effects of CytoSorb Hemoperfusion on the Development on Immunoparalysis (EndoSorb)

An Open-label Randomized Controlled Experimental Endotoxemia Study on the Effects of the Cytokine-adsorber CytoSorb on the Development of Immunoparalysis in Humans

Sponsor: CytoSorbents Europe GmbH

Updated 7 times since 2020 Last updated: Dec 20, 2022 Started: Sep 16, 2020 Primary completion: Oct 19, 2022 Completion: Oct 19, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04643639, this PHASE3 trial focuses on Blood Purification and Hemoperfusion and remains completed. Sponsored by CytoSorbents Europe GmbH, it has been updated 7 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotRecruiting~Jan 2021 – ~Apr 2021 · 3 months · monthly snapshotRecruiting~Apr 2021 – ~Mar 2022 · 11 months · monthly snapshotRecruiting~Mar 2022 – ~Jan 2023 · 10 months · monthly snapshotRecruiting~Jan 2023 – ~Jul 2024 · 18 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 22 months · monthly snapshotCompleted

Change History

7 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE3

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE3

  3. Jan 2023 — Jul 2024 [monthly]

    Completed PHASE3

    Status: RecruitingCompleted

  4. Mar 2022 — Jan 2023 [monthly]

    Recruiting PHASE3

  5. Apr 2021 — Mar 2022 [monthly]

    Recruiting PHASE3

Show 2 earlier versions
  1. Jan 2021 — Apr 2021 [monthly]

    Recruiting PHASE3

  2. Dec 2020 — Jan 2021 [monthly]

    Recruiting PHASE3

    First recorded

Sep 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • CytoSorbents Europe GmbH
  • Radboud University Medical Center
Data source: Radboud University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations