deltatrials
Unknown NA INTERVENTIONAL 3-arm NCT04644744

Hypothermic Oxygenated (HOPE) Versus Normothermic Machine Perfusion (NMP) in Human Liver Transplantation (HOPE-NMP)

End-ischemic Hypothermic Oxygenated (HOPE) vs. Normothermic Machine Perfusion (NMP) Compared to Conventional Cold Storage in Donation After Brain Death Liver Transplantation; a Prospective Multicentre Randomized Controlled Trial (HOPE-NMP)

Sponsor: Charite University, Berlin, Germany

Updated 10 times since 2020 Last updated: Jul 21, 2022 Started: Jan 14, 2021 Primary completion: Dec 31, 2023 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates Hepatocellular Injury and Liver Transplant Disorder and is currently ongoing. Charite University, Berlin, Germany leads this study, which shows 10 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Dec 2020 – ~Jan 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshotNot Yet Recruiting~Feb 2021 – ~Apr 2021 · 59 days · monthly snapshotRecruiting~Apr 2021 – ~Jan 2022 · 9 months · monthly snapshotRecruiting~Jan 2022 – ~Sep 2022 · 8 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshotRecruiting~Jan 2025 – ~Sep 2025 · 8 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotUnknown

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Unknown NA

  2. Jan 2025 — Sep 2025 [monthly]

    Unknown NA

    Status: RecruitingUnknown

  3. Sep 2024 — Jan 2025 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Sep 2022 — Jul 2024 [monthly]

    Recruiting NA

    Status: Active Not RecruitingRecruiting

Show 5 earlier versions
  1. Jan 2022 — Sep 2022 [monthly]

    Active Not Recruiting NA

    Status: RecruitingActive Not Recruiting

  2. Apr 2021 — Jan 2022 [monthly]

    Recruiting NA

  3. Feb 2021 — Apr 2021 [monthly]

    Recruiting NA

    Status: Not Yet RecruitingRecruiting

  4. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting NA

  5. Dec 2020 — Jan 2021 [monthly]

    Not Yet Recruiting NA

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Charite University, Berlin, Germany
Data source: Charite University, Berlin, Germany

For direct contact, visit the study record on ClinicalTrials.gov .