deltatrials
Active Not Recruiting PHASE1 INTERVENTIONAL 4-arm NCT04644770

A Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

A Phase 1 Study of JNJ-69086420, an Actinium-225-Labeled Antibody Targeting Human Kallikrein-2 (hK2) for Advanced Prostate Cancer

Sponsor: Janssen Research & Development, LLC

Updated 18 times since 2024 Last updated: Mar 12, 2026 Started: Nov 12, 2020 Primary completion: Jan 15, 2027 Completion: Jan 15, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04644770, this PHASE1 trial focuses on Adenocarcinoma and Prostatic Neoplasms and remains ongoing. Sponsored by Janssen Research & Development, LLC, it has been updated 18 times since 2020, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshotRecruiting~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~Apr 2025 · 31 days · monthly snapshot~Apr 2025 – ~May 2025 · 30 days · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Jul 2025 · 30 days · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Dec 2025 · 30 days · monthly snapshot~Dec 2025 – ~Jan 2026 · 31 days · monthly snapshot~Jan 2026 – ~Feb 2026 · 31 days · monthly snapshot~Feb 2026 – ~Mar 2026 · 28 days · monthly snapshot~Mar 2026 – present · 56 days · monthly snapshotActive Not Recruiting

Change History

18 versions recorded
  1. Mar 2026 — Present [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2026 — Mar 2026 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2026 — Feb 2026 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  4. Dec 2025 — Jan 2026 [monthly]

    Recruiting PHASE1

  5. Nov 2025 — Dec 2025 [monthly]

    Recruiting PHASE1

Show 13 earlier versions
  1. Oct 2025 — Nov 2025 [monthly]

    Recruiting PHASE1

  2. Sep 2025 — Oct 2025 [monthly]

    Recruiting PHASE1

  3. Aug 2025 — Sep 2025 [monthly]

    Recruiting PHASE1

  4. Jul 2025 — Aug 2025 [monthly]

    Recruiting PHASE1

  5. Jun 2025 — Jul 2025 [monthly]

    Recruiting PHASE1

  6. May 2025 — Jun 2025 [monthly]

    Recruiting PHASE1

  7. Apr 2025 — May 2025 [monthly]

    Recruiting PHASE1

  8. Mar 2025 — Apr 2025 [monthly]

    Recruiting PHASE1

  9. Feb 2025 — Mar 2025 [monthly]

    Recruiting PHASE1

  10. Jan 2025 — Feb 2025 [monthly]

    Recruiting PHASE1

  11. Nov 2024 — Jan 2025 [monthly]

    Recruiting PHASE1

  12. Oct 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  13. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

    First recorded

Nov 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Research & Development, LLC
Data source: Janssen Research & Development, LLC

For direct contact, visit the study record on ClinicalTrials.gov .