How Does the Addition of Adductor Canal Block to Local Infiltration Affect Recovery in Patients Undergoing Total Knee Arthroplasty? A Feasibility Study. (TRUE KnORTH)
Total Regional Anesthesia Techniques Resulting in up and Early Discharge Following Knee Surgery: An Opioid Reduction Plan for Transitional Pain at Home.
Sponsor: Dedicated Anesthesia Research Enhancement Grant
A NA clinical study on Arthritis Knee and Knee Disease, this trial is completed. The trial is conducted by Dedicated Anesthesia Research Enhancement Grant and has accumulated 7 data snapshots since 2020. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.
Study Description(click to expand)This study is a double blinded, randomized control trial. In order to create a blinded study, each participant will receive two injections; a single shot adductor canal block (ACB) and a periarticular injection (PI). All syringes will be non-identifiable to the surgeon, anesthetist and the patient.
Specifically, the two arms are:
Arm 1: PI (Ropivacaine + Ketorolac + Epinepherine) + ACB (Ropivacaine)
Arm 2: PI (Ropivacaine + Ketorolac + Epinepherine) + ACB (Normal Saline)
The aim of this study is to investigate whether combining these two techniques have an added benefit, compared to periarticular injection alone. The investigators hypothesize that the addition of an adductor canal block will translate to a superior quality of recovery, as well as an improvement in functional return, discharge readiness and less short-term and long-term post-operative narcotic use.
This study is a double blinded, randomized control trial. In order to create a blinded study, each participant will receive two injections; a single shot adductor canal block (ACB) and a periarticular injection (PI). All syringes will be non-identifiable to the surgeon, anesthetist and the patient.
Specifically, the two arms are:
Arm 1: PI (Ropivacaine + Ketorolac + Epinepherine) + ACB (Ropivacaine)
Arm 2: PI (Ropivacaine + Ketorolac + Epinepherine) + ACB (Normal Saline)
The aim of this study is to investigate whether combining these two techniques have an added benefit, compared to periarticular injection alone. The investigators hypothesize that the addition of an adductor canal block will translate to a superior quality of recovery, as well as an improvement in functional return, discharge readiness and less short-term and long-term post-operative narcotic use.
Status Flow
Change History
7 versions recorded-
Jan 2026 — Present [monthly]
Completed NA
-
Sep 2025 — Present [monthly]
Completed NA
-
Sep 2024 — Sep 2025 [monthly]
Completed NA
-
Jul 2024 — Sep 2024 [monthly]
Completed NA
-
Jun 2023 — Jul 2024 [monthly]
Completed NA
Status: Unknown Status → Completed
▶ Show 2 earlier versions
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Dec 2022 — Jun 2023 [monthly]
Unknown Status NA
Status: Recruiting → Unknown Status
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Jan 2021 — Dec 2022 [monthly]
Recruiting NA
First recorded
Nov 2020
Trial started
Per CT.gov start date — pre-dates our first snapshot
Eligibility Summary
No eligibility information available.
Contact Information
- Dedicated Anesthesia Research Enhancement Grant
- Health Sciences North Research Institute
For direct contact, visit the study record on ClinicalTrials.gov .