deltatrials
Terminated PHASE2 INTERVENTIONAL 2-arm NCT04684394

A Multiple Dose Study of Repeat Intravitreal Injections of GEM103 in Neovascular Age-related Macular Degeneration

A Multicenter, Multiple-Dose Study in Neovascular Age-related Macular Degeneration (nAMD) to Evaluate the Safety, Tolerability, Pharmacodynamics, Immunogenicity, and Clinical Effect of Repeat Intravitreal (IVT) Injections of GEM103 as an Adjunct to Standard of Care Aflibercept Therapy

Sponsor: Gemini Therapeutics, Inc.

Updated 9 times since 2021 Last updated: Oct 4, 2022 Started: Dec 29, 2020 Primary completion: Jan 10, 2022 Completion: Feb 18, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Sponsor decision

Other terminated trials from Gemini Therapeutics, Inc.

More terminations from Gemini Therapeutics, Inc.

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Listed as NCT04684394, this PHASE2 trial focuses on Macular Degeneration and Neovascular Age-related Macular Degeneration and remains terminated or withdrawn. Sponsored by Gemini Therapeutics, Inc., it has been updated 9 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jan 2021 – ~Mar 2021 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshotRecruiting~Apr 2021 – ~May 2021 · 30 days · monthly snapshotRecruiting~May 2021 – ~Jun 2021 · 31 days · monthly snapshotRecruiting~Jun 2021 – ~Apr 2022 · 10 months · monthly snapshotActive Not Recruiting~Apr 2022 – ~Nov 2022 · 7 months · monthly snapshotCompleted~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 23 months · monthly snapshotTerminated

Change History

9 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated PHASE2

  3. Nov 2022 — Jul 2024 [monthly]

    Terminated PHASE2

    Status: CompletedTerminated

  4. Apr 2022 — Nov 2022 [monthly]

    Completed PHASE2

    Status: Active Not RecruitingCompleted

  5. Jun 2021 — Apr 2022 [monthly]

    Active Not Recruiting PHASE2

    Status: RecruitingActive Not Recruiting

Show 4 earlier versions
  1. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE2

  2. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

  3. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2

    Status: Not Yet RecruitingRecruiting

  4. Jan 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Dec 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Gemini Therapeutics, Inc.
Data source: Gemini Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .