deltatrials
Active Not Recruiting OBSERVATIONAL NCT04687969

Multimodal Machine Learning Characterization of Solid Tumors

Multimodal PET/MRI Machine Learning Approaches for Characterization of Solid Tumors

Sponsor: Ciprian Catana, MD, PhD

Updated 13 times since 2021 Last updated: Sep 22, 2025 Started: Oct 23, 2022 Primary completion: Aug 31, 2024 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A observational or N/A phase clinical study on Adenocarcinoma of Prostate and Glioma, this trial is ongoing. The trial is conducted by Ciprian Catana, MD, PhD and has accumulated 13 data snapshots since 2022. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Study Description(click to expand)

This is an observational imaging study to evaluate the value of multimodal \[18F\]DCFPyL positron emission tomography and magnetic resonance imaging (PET/MRI) for solid tumor characterization and disease staging. This research study involves: * Screening visit, and 1-3 study Multimodal \[18F\]DCFPyL PET/MRI visits * Two cohorts of participants will be enrolled in this study: primary prostate cancer patients and patients with known or suspected solid tumors (hepatocellular carcinoma, glioma, clear cell renal carcinoma) * It is expected that about 135 people will take part in this research study * The PET dye used in this study is called \[18F\]DCFPyL. \[18F\]DCFPyL is approved by the U.S. Food and Drug administration (FDA). * The PET/MRI scanner was approved by the U.S. FDA.

This is an observational imaging study to evaluate the value of multimodal \[18F\]DCFPyL positron emission tomography and magnetic resonance imaging (PET/MRI) for solid tumor characterization and disease staging.

This research study involves:

* Screening visit, and 1-3 study Multimodal \[18F\]DCFPyL PET/MRI visits * Two cohorts of participants will be enrolled in this study: primary prostate cancer patients and patients with known or suspected solid tumors (hepatocellular carcinoma, glioma, clear cell renal carcinoma) * It is expected that about 135 people will take part in this research study

* The PET dye used in this study is called \[18F\]DCFPyL. \[18F\]DCFPyL is approved by the U.S. Food and Drug administration (FDA). * The PET/MRI scanner was approved by the U.S. FDA.

Status Flow

~Jan 2021 – ~Feb 2021 · 31 days · monthly snapshot~Feb 2021 – ~Jun 2021 · 4 months · monthly snapshot~Jun 2021 – ~Dec 2021 · 6 months · monthly snapshot~Dec 2021 – ~Feb 2022 · 2 months · monthly snapshot~Feb 2022 – ~May 2022 · 3 months · monthly snapshot~May 2022 – ~Sep 2022 · 4 months · monthly snapshot~Sep 2022 – ~Apr 2023 · 7 months · monthly snapshot~Apr 2023 – ~Apr 2024 · 12 months · monthly snapshot~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshot~Oct 2025 – present · 6 months · monthly snapshot~Jan 2026 – present · 3 months · monthly snapshot

Change History

13 versions recorded
  1. Jan 2026 — Present [monthly]

    Active Not Recruiting

  2. Oct 2025 — Present [monthly]

    Active Not Recruiting

    Status: RecruitingActive Not Recruiting

  3. Sep 2024 — Oct 2025 [monthly]

    Recruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting

  5. Apr 2024 — Jul 2024 [monthly]

    Recruiting

Show 8 earlier versions
  1. Apr 2023 — Apr 2024 [monthly]

    Recruiting

  2. Sep 2022 — Apr 2023 [monthly]

    Recruiting

  3. May 2022 — Sep 2022 [monthly]

    Recruiting

  4. Feb 2022 — May 2022 [monthly]

    Recruiting

  5. Dec 2021 — Feb 2022 [monthly]

    Recruiting

    Status: Not Yet RecruitingRecruiting

  6. Jun 2021 — Dec 2021 [monthly]

    Not Yet Recruiting

  7. Feb 2021 — Jun 2021 [monthly]

    Not Yet Recruiting

  8. Jan 2021 — Feb 2021 [monthly]

    Not Yet Recruiting

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Ciprian Catana, MD, PhD
  • National Cancer Institute (NCI)
Data source: Massachusetts General Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations