deltatrials
Terminated PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT04695977

CMP-001 in Combination With Nivolumab Compared to Nivolumab Monotherapy in Subjects With Advanced Melanoma

A Randomized, Open-label, Active-control, Phase 2/3 Study of First-line Intratumoral CMP-001 in Combination With Intravenous Nivolumab Compared to Nivolumab Monotherapy in Subjects With Unresectable or Metastatic Melanoma

Sponsor: Bristol-Myers Squibb

Updated 18 times since 2021 Last updated: Aug 15, 2025 Started: Feb 24, 2021 Primary completion: Jul 22, 2024 Completion: Jul 22, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Business Decision

Listed as NCT04695977, this PHASE2/PHASE3 trial focuses on Advanced Melanoma and Melanoma and remains terminated or withdrawn. Sponsored by Bristol-Myers Squibb, it has been updated 18 times since 2021, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Feb 2021 – ~Mar 2021 · 28 days · monthly snapshot~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Sep 2021 · 5 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Feb 2023 · 5 months · monthly snapshot~Feb 2023 – ~Mar 2024 · 13 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshot~Nov 2024 – ~Oct 2025 · 11 months · monthly snapshot~Oct 2025 – present · 9 months · monthly snapshot

Change History

18 versions recorded
  1. Oct 2025 — Present [monthly]

    Terminated PHASE2/PHASE3

  2. Nov 2024 — Oct 2025 [monthly]

    Terminated PHASE2/PHASE3

    Status: CompletedTerminated

  3. Sep 2024 — Nov 2024 [monthly]

    Completed PHASE2/PHASE3

    Status: Active Not RecruitingCompleted

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE2/PHASE3

    Phase: PHASE2_PHASE3PHASE2/PHASE3

  5. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

Show 13 earlier versions
  1. Feb 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE2_PHASE3

  2. Sep 2022 — Feb 2023 [monthly]

    Active Not Recruiting PHASE2_PHASE3

    Status: RecruitingActive Not Recruiting

  3. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE2_PHASE3

  4. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE2_PHASE3

  5. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE2_PHASE3

  6. Feb 2022 — Apr 2022 [monthly]

    Recruiting PHASE2_PHASE3

  7. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE2_PHASE3

  8. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE2_PHASE3

  9. Oct 2021 — Dec 2021 [monthly]

    Recruiting PHASE2_PHASE3

  10. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE2_PHASE3

  11. Apr 2021 — Sep 2021 [monthly]

    Recruiting PHASE2_PHASE3

  12. Mar 2021 — Apr 2021 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

  13. Feb 2021 — Mar 2021 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
  • Regeneron Pharmaceuticals
Data source: Regeneron Pharmaceuticals

For direct contact, visit the study record on ClinicalTrials.gov .