deltatrials
Completed PHASE1 INTERVENTIONAL 3-arm NCT04705922

Relative Bioavailability Study and Food Effect Study of TT-00420 (Tinengotinib) Capsule and Tablet Formulations in Healthy Volunteers

A Phase I, Single-Center, Open-Label, 3-Way Crossover, Randomized Single Dose Study to Evaluate the Food Effect on the Pharmacokinetics of TT-00420 Tablet and to Determine the Relative Bioavailability of TT-00420 Tablet Versus TT-00420 Capsule in Adult Healthy Volunteers

Sponsor: TransThera Sciences (Nanjing), Inc.

Conditions Healthy
Updated 8 times since 2021 Last updated: Dec 28, 2023 Started: Dec 29, 2020 Primary completion: Mar 7, 2021 Completion: Jul 23, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04705922, this PHASE1 trial focuses on Healthy and remains completed. Sponsored by TransThera Sciences (Nanjing), Inc., it has been updated 8 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Feb 2021 – ~May 2021 · 3 months · monthly snapshotRecruiting~May 2021 – ~Jun 2021 · 31 days · monthly snapshotActive Not Recruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotActive Not Recruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotCompleted~Oct 2021 – ~Feb 2024 · 28 months · monthly snapshotCompleted~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – present · 24 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Sep 2024 — Present [monthly]

    Completed PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  3. Feb 2024 — Jul 2024 [monthly]

    Completed PHASE1

  4. Oct 2021 — Feb 2024 [monthly]

    Completed PHASE1

  5. Sep 2021 — Oct 2021 [monthly]

    Completed PHASE1

    Status: Active Not RecruitingCompleted

Show 3 earlier versions
  1. Jun 2021 — Sep 2021 [monthly]

    Active Not Recruiting PHASE1

  2. May 2021 — Jun 2021 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Feb 2021 — May 2021 [monthly]

    Recruiting PHASE1

    First recorded

Dec 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • TransThera Sciences (Nanjing), Inc.
Data source: TransThera Sciences (Nanjing), Inc.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations