deltatrials
Terminated PHASE4 INTERVENTIONAL 2-arm NCT04710914

Comparison of Extubation Delay After Prolonged Sedation (ISOREA)

Comparison of Extubation Delay After Prolonged Sedation With Inhaled Isoflurane Using the MIRUS® Device or Continuous Intravenous Midazolam in Patients With Septic Shock in Intensive Care

Sponsor: University Hospital, Rouen

Conditions Septic Shock
Updated 5 times since 2021 Last updated: Feb 5, 2026 Started: Dec 15, 2020 Primary completion: Dec 26, 2020 Completion: Dec 26, 2020
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

COVID epidemic and sedation practices that have completely changed: the standard sedative is now propofol rather than midazolam.

Listed as NCT04710914, this PHASE4 trial focuses on Septic Shock and remains terminated or withdrawn. Sponsored by University Hospital, Rouen, it has been updated 5 times since 2020, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Feb 2021 – ~May 2023 · 27 months · monthly snapshotRecruiting~May 2023 – ~Jul 2024 · 14 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotUnknown~Feb 2026 – present · 7 months · monthly snapshotTerminated

Change History

5 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE4

    Status: UnknownTerminated

  2. Sep 2024 — Feb 2026 [monthly]

    Unknown PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE4

    Status: Unknown StatusUnknown

  4. May 2023 — Jul 2024 [monthly]

    Unknown Status PHASE4

    Status: RecruitingUnknown Status

  5. Feb 2021 — May 2023 [monthly]

    Recruiting PHASE4

    First recorded

Dec 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • University Hospital, Rouen
Data source: University Hospital, Rouen

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations