deltatrials
Recruiting PHASE1 INTERVENTIONAL 1-arm NCT04715191

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressed in T Cells for Pediatric Solid Tumors

Interleukin-15 and -21 Armored Glypican-3-specific Chimeric Antigen Receptor Expressing Autologous T Cells as an Immunotherapy for Children With Solid Tumors (CARE)

Sponsor: Baylor College of Medicine

Updated 11 times since 2021 Last updated: Apr 30, 2025 Started: May 24, 2024 Primary completion: Aug 1, 2026 Completion: Jul 3, 2041
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE1 clinical study on Liposarcoma and Liver Cancer, this trial is actively recruiting participants. The trial is conducted by Baylor College of Medicine and has accumulated 11 data snapshots since 2024. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Feb 2021 – ~Dec 2021 · 10 months · monthly snapshotNot Yet Recruiting~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshotNot Yet Recruiting~Jan 2022 – ~Aug 2023 · 19 months · monthly snapshotNot Yet Recruiting~Aug 2023 – ~Nov 2023 · 3 months · monthly snapshotNot Yet Recruiting~Nov 2023 – ~Mar 2024 · 4 months · monthly snapshotNot Yet Recruiting~Mar 2024 – ~Jun 2024 · 3 months · monthly snapshotNot Yet Recruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotNot Yet Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotNot Yet Recruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~Jun 2025 · 8 months · monthly snapshotRecruiting~Jun 2025 – present · 13 months · monthly snapshotRecruiting

Change History

11 versions recorded
  1. Jun 2025 — Present [monthly]

    Recruiting PHASE1

  2. Oct 2024 — Jun 2025 [monthly]

    Recruiting PHASE1

  3. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  4. Jul 2024 — Sep 2024 [monthly]

    Not Yet Recruiting PHASE1

  5. Jun 2024 — Jul 2024 [monthly]

    Not Yet Recruiting PHASE1

Show 6 earlier versions
  1. Mar 2024 — Jun 2024 [monthly]

    Not Yet Recruiting PHASE1

  2. Nov 2023 — Mar 2024 [monthly]

    Not Yet Recruiting PHASE1

  3. Aug 2023 — Nov 2023 [monthly]

    Not Yet Recruiting PHASE1

  4. Jan 2022 — Aug 2023 [monthly]

    Not Yet Recruiting PHASE1

  5. Dec 2021 — Jan 2022 [monthly]

    Not Yet Recruiting PHASE1

  6. Feb 2021 — Dec 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Baylor College of Medicine
  • Center for Cell and Gene Therapy, Baylor College of Medicine
Data source: Baylor College of Medicine

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations