deltatrials
Unknown PHASE3 INTERVENTIONAL 2-arm NCT04723004

Evaluate the Safety and Efficacy of Toripalimab Combined With Bevacizumab Versus Sorafenib Therapy for HCC

A Randomized, Open-label, Multi-center Phase III Clinical Study to Evaluate the Safety and Efficacy of Toripalimab (JS001) Combined With Bevacizumab Versus Sorafenib as First-line Therapy for Advanced Hepatocellular Carcinoma

Sponsor: Shanghai Junshi Bioscience Co., Ltd.

Updated 7 times since 2021 Last updated: Aug 9, 2023 Started: Oct 15, 2020 Primary completion: Oct 31, 2023 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04723004, this PHASE3 trial focuses on Advanced Hepatocellular Carcinoma (HCC) and remains ongoing. Sponsored by Shanghai Junshi Bioscience Co., Ltd., it has been updated 7 times since 2020, reflecting limited change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Feb 2021 – ~Jul 2022 · 17 months · monthly snapshotRecruiting~Jul 2022 – ~Sep 2023 · 14 months · monthly snapshotActive Not Recruiting~Sep 2023 – ~Jul 2024 · 10 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotActive Not Recruiting~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshotActive Not Recruiting~Oct 2025 – present · 10 months · monthly snapshotUnknown

Change History

7 versions recorded
  1. Oct 2025 — Present [monthly]

    Unknown PHASE3

    Status: Active Not RecruitingUnknown

  2. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE3

  3. Sep 2024 — Sep 2025 [monthly]

    Active Not Recruiting PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE3

  5. Sep 2023 — Jul 2024 [monthly]

    Active Not Recruiting PHASE3

Show 2 earlier versions
  1. Jul 2022 — Sep 2023 [monthly]

    Active Not Recruiting PHASE3

    Status: RecruitingActive Not Recruiting

  2. Feb 2021 — Jul 2022 [monthly]

    Recruiting PHASE3

    First recorded

Oct 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Shanghai Junshi Bioscience Co., Ltd.
Data source: Shanghai Junshi Bioscience Co., Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .