Recruiting OBSERVATIONAL NCT04725422

CHronic Nonbacterial Osteomyelitis International Registry (CHOIR)

Sponsor: Alder Hey Children's NHS Foundation Trust

Conditions Chronic Nonbacterial Osteomyelitis Chronic Recurrent Multifocal Osteomyelitis

Interventions Adalimumab Certolizumab Etanercept Golimumab Infliximab Leflunomide Methotrexate NSAID Pamidronate Sulfasalazine Zoledronic acid

Updated 9 times since 2021 Last updated: Jul 27, 2024 Started: Aug 1, 2018 Primary completion: Aug 31, 2028 Completion: Aug 31, 2050

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04725422, this observational or N/A phase trial focuses on Chronic Nonbacterial Osteomyelitis and Chronic Recurrent Multifocal Osteomyelitis and remains actively recruiting participants. Sponsored by Alder Hey Children's NHS Foundation Trust, it has been updated 9 times since 2018, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

Change History

9 versions recorded

Feb 2026 — Present [monthly]

Recruiting
Dec 2025 — Feb 2026 [monthly]

Recruiting
Mar 2025 — Dec 2025 [monthly]

Recruiting
Sep 2024 — Mar 2025 [monthly]

Recruiting
Aug 2024 — Sep 2024 [monthly]

Recruiting

▶ Show 4 earlier versions

Jul 2024 — Aug 2024 [monthly]

Recruiting
Feb 2024 — Jul 2024 [monthly]

Recruiting
Oct 2021 — Feb 2024 [monthly]

Recruiting
Feb 2021 — Oct 2021 [monthly]

Recruiting

First recorded

Aug 2018

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Alder Hey Children's NHS Foundation Trust
Ann & Robert H Lurie Children's Hospital of Chicago
Bambino Gesù Children's Hospital, Rome, Italy
Boston Children's Hospital, Boston, MA, USA
Hacettepe University
Hospital for Special Surgery, New York
Joseph M Sanzari Children's Hospital, Hackensack University Medical Center, Hackensack, NJ, USA
Mansoura University
Meyer Children's Hospital, Florence, Italy
Palacky University Olomouc Institute of Molecular and Translational Medicine, Olomouc, Czechia
Riley Children's Hospital, Indianapolis, IN, USA
Royal Children's Hospital
Seattle Children's Hospital
University of British Columbia, Vancouver, BC, Canada
University of Calgary, Calgary, Alberta, Canada
University of Iowa Carver College of Medicine, Iowa City, IA, USA
University of North Carolina, Chapel Hill, NC, USA
University of Utah, Salt Lake City, UT, USA

Data source: Seattle Children's Hospital

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Seattle, United States