Active Not Recruiting NA INTERVENTIONAL 1-arm NCT04736121

Selective Internal Radiation Therapy (SIRT) Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients (DOORwaY90)

A Prospective, Multicenter, Open-label Single Arm Study Evaluating the Safety & Efficacy of Selective Internal Radiation Therapy Using SIR-Spheres® Y-90 Resin Microspheres on DoR & ORR in Unresectable Hepatocellular Carcinoma Patients

Sponsor: Bright Research Partners

Conditions BCLC Stage A Hepatocellular Carcinoma BCLC Stage B Hepatocellular Carcinoma BCLC Stage C Hepatocellular Carcinoma Unresectable Hepatocellular Carcinoma

Interventions Resin microspheres containing yttrium-90 (Y-90)

Updated 26 times since 2021 Last updated: Jan 30, 2026 Started: May 28, 2021 Primary completion: Aug 14, 2025 Completion: Sep 30, 2026

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This NA trial investigates BCLC Stage A Hepatocellular Carcinoma and BCLC Stage B Hepatocellular Carcinoma and is currently ongoing. Bright Research Partners leads this study, which shows 26 recorded versions since 2021 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

Change History

26 versions recorded

Feb 2026 — Present [monthly]

Active Not Recruiting NA
Mar 2025 — Feb 2026 [monthly]

Active Not Recruiting NA
Dec 2024 — Mar 2025 [monthly]

Active Not Recruiting NA
Nov 2024 — Dec 2024 [monthly]

Active Not Recruiting NA
Sep 2024 — Nov 2024 [monthly]

Active Not Recruiting NA

Status: Recruiting → Active Not Recruiting

▶ Show 21 earlier versions

Aug 2024 — Sep 2024 [monthly]

Recruiting NA
Jul 2024 — Aug 2024 [monthly]

Recruiting NA
Apr 2024 — Jul 2024 [monthly]

Recruiting NA
Mar 2024 — Apr 2024 [monthly]

Recruiting NA
Feb 2024 — Mar 2024 [monthly]

Recruiting NA
Sep 2023 — Feb 2024 [monthly]

Recruiting NA
Jun 2023 — Sep 2023 [monthly]

Recruiting NA
May 2023 — Jun 2023 [monthly]

Recruiting NA
Sep 2022 — May 2023 [monthly]

Recruiting NA
Jul 2022 — Sep 2022 [monthly]

Recruiting NA
Jun 2022 — Jul 2022 [monthly]

Recruiting NA
May 2022 — Jun 2022 [monthly]

Recruiting NA
Apr 2022 — May 2022 [monthly]

Recruiting NA
Mar 2022 — Apr 2022 [monthly]

Recruiting NA
Jan 2022 — Mar 2022 [monthly]

Recruiting NA
Dec 2021 — Jan 2022 [monthly]

Recruiting NA
Nov 2021 — Dec 2021 [monthly]

Recruiting NA
Oct 2021 — Nov 2021 [monthly]

Recruiting NA
Sep 2021 — Oct 2021 [monthly]

Recruiting NA

Status: Not Yet Recruiting → Recruiting
Apr 2021 — Sep 2021 [monthly]

Not Yet Recruiting NA
Mar 2021 — Apr 2021 [monthly]

Not Yet Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Bright Research Partners
Sirtex Medical

Data source: Sirtex Medical

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Atlanta, United States , Boston, United States , Burlington, United States , Chapel Hill, United States , Cincinnati, United States , Cleveland, United States , Dallas, United States , Houston, United States , Kansas City, United States , Los Angeles, United States and 9 more locations