deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT04773522

A Study of JNJ-64407564 in Japanese Participants With Relapsed or Refractory Multiple Myeloma

A Phase 1 Study of JNJ-64407564, a Humanized GPRC5D * CD3 Bispecific Antibody in Japanese Subjects With Relapsed or Refractory Multiple Myeloma

Sponsor: Janssen Pharmaceutical K.K.

Conditions Multiple Myeloma
Interventions Talquetamab
Updated 48 times since 2021 Last updated: Sep 30, 2025 Started: May 20, 2021 Primary completion: Oct 14, 2022 Completion: Sep 4, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Multiple Myeloma and is currently completed. Janssen Pharmaceutical K.K. leads this study, which shows 48 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Mar 2021 – ~Apr 2021 · 31 days · monthly snapshot~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshot~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshot~Oct 2021 – ~Nov 2021 · 31 days · monthly snapshot~Nov 2021 – ~Dec 2021 · 30 days · monthly snapshot~Dec 2021 – ~Jan 2022 · 31 days · monthly snapshot~Jan 2022 – ~Feb 2022 · 31 days · monthly snapshot~Feb 2022 – ~Mar 2022 · 28 days · monthly snapshot~Mar 2022 – ~Apr 2022 · 31 days · monthly snapshot~Apr 2022 – ~May 2022 · 30 days · monthly snapshot~May 2022 – ~Jun 2022 · 31 days · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Jan 2023 · 31 days · monthly snapshot~Jan 2023 – ~Feb 2023 · 31 days · monthly snapshot~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshot~Mar 2023 – ~Apr 2023 · 31 days · monthly snapshot~Apr 2023 – ~May 2023 · 30 days · monthly snapshot~May 2023 – ~Jun 2023 · 31 days · monthly snapshot~Jun 2023 – ~Jul 2023 · 30 days · monthly snapshot~Jul 2023 – ~Aug 2023 · 31 days · monthly snapshot~Aug 2023 – ~Sep 2023 · 31 days · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Nov 2023 · 31 days · monthly snapshot~Nov 2023 – ~Dec 2023 · 30 days · monthly snapshot~Dec 2023 – ~Jan 2024 · 31 days · monthly snapshot~Jan 2024 – ~Feb 2024 · 31 days · monthly snapshot~Feb 2024 – ~Mar 2024 · 29 days · monthly snapshot~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshot~Apr 2024 – ~May 2024 · 30 days · monthly snapshot~May 2024 – ~Jun 2024 · 31 days · monthly snapshot~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshot~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshot~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~Nov 2024 · 31 days · monthly snapshot~Nov 2024 – ~Jan 2025 · 2 months · monthly snapshot~Jan 2025 – ~Feb 2025 · 31 days · monthly snapshot~Feb 2025 – ~Mar 2025 · 28 days · monthly snapshot~Mar 2025 – ~May 2025 · 2 months · monthly snapshot~May 2025 – ~Jun 2025 · 31 days · monthly snapshot~Jun 2025 – ~Aug 2025 · 2 months · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Nov 2025 · 2 months · monthly snapshot~Nov 2025 – present · 7 months · monthly snapshot

Change History

48 versions recorded

  1. Nov 2025 — Present [monthly]

    Completed PHASE1

    Status: Active Not Recruiting → Completed

  2. Sep 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Jun 2025 — Aug 2025 [monthly]

    Active Not Recruiting PHASE1

  5. May 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1

▶ Show 43 earlier versions

  1. Mar 2025 — May 2025 [monthly]

    Active Not Recruiting PHASE1

  2. Feb 2025 — Mar 2025 [monthly]

    Active Not Recruiting PHASE1

  3. Jan 2025 — Feb 2025 [monthly]

    Active Not Recruiting PHASE1

  4. Nov 2024 — Jan 2025 [monthly]

    Active Not Recruiting PHASE1

  5. Oct 2024 — Nov 2024 [monthly]

    Active Not Recruiting PHASE1

  6. Sep 2024 — Oct 2024 [monthly]

    Active Not Recruiting PHASE1

  7. Aug 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1

  8. Jul 2024 — Aug 2024 [monthly]

    Active Not Recruiting PHASE1

  9. Jun 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1

  10. May 2024 — Jun 2024 [monthly]

    Active Not Recruiting PHASE1

  11. Apr 2024 — May 2024 [monthly]

    Active Not Recruiting PHASE1

  12. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE1

  13. Feb 2024 — Mar 2024 [monthly]

    Active Not Recruiting PHASE1

  14. Jan 2024 — Feb 2024 [monthly]

    Active Not Recruiting PHASE1

    Status: Recruiting → Active Not Recruiting

  15. Dec 2023 — Jan 2024 [monthly]

    Recruiting PHASE1

  16. Nov 2023 — Dec 2023 [monthly]

    Recruiting PHASE1

  17. Oct 2023 — Nov 2023 [monthly]

    Recruiting PHASE1

  18. Sep 2023 — Oct 2023 [monthly]

    Recruiting PHASE1

  19. Aug 2023 — Sep 2023 [monthly]

    Recruiting PHASE1

  20. Jul 2023 — Aug 2023 [monthly]

    Recruiting PHASE1

  21. Jun 2023 — Jul 2023 [monthly]

    Recruiting PHASE1

  22. May 2023 — Jun 2023 [monthly]

    Recruiting PHASE1

  23. Apr 2023 — May 2023 [monthly]

    Recruiting PHASE1

  24. Mar 2023 — Apr 2023 [monthly]

    Recruiting PHASE1

  25. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1

  26. Jan 2023 — Feb 2023 [monthly]

    Recruiting PHASE1

  27. Dec 2022 — Jan 2023 [monthly]

    Recruiting PHASE1

  28. Nov 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

  29. Sep 2022 — Nov 2022 [monthly]

    Recruiting PHASE1

  30. Jul 2022 — Sep 2022 [monthly]

    Recruiting PHASE1

  31. Jun 2022 — Jul 2022 [monthly]

    Recruiting PHASE1

  32. May 2022 — Jun 2022 [monthly]

    Recruiting PHASE1

  33. Apr 2022 — May 2022 [monthly]

    Recruiting PHASE1

  34. Mar 2022 — Apr 2022 [monthly]

    Recruiting PHASE1

  35. Feb 2022 — Mar 2022 [monthly]

    Recruiting PHASE1

  36. Jan 2022 — Feb 2022 [monthly]

    Recruiting PHASE1

  37. Dec 2021 — Jan 2022 [monthly]

    Recruiting PHASE1

  38. Nov 2021 — Dec 2021 [monthly]

    Recruiting PHASE1

  39. Oct 2021 — Nov 2021 [monthly]

    Recruiting PHASE1

  40. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE1

  41. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE1

    Status: Not Yet Recruiting → Recruiting

  42. Apr 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE1

  43. Mar 2021 — Apr 2021 [monthly]

    Not Yet Recruiting PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Janssen Pharmaceutical K.K.
Data source: Janssen Pharmaceutical K.K.

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations