deltatrials
Terminated EARLY_PHASE1 INTERVENTIONAL 1-arm NCT04777708

BO-112 and Pembrolizumab for the Treatment of PD-1/PD-L1 Refractory Liver Cancer

Pilot Feasibility Study of Intratumoral BO-112 in Combination With Pembrolizumab for Advanced Hepatocellular Carcinoma

Sponsor: Highlight Therapeutics

Updated 10 times since 2021 Last updated: Mar 22, 2023 Started: Oct 13, 2021 Primary completion: Mar 13, 2023 Completion: Mar 13, 2023
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Withdrawn by sponsor

Other terminated trials from Highlight Therapeutics

More terminations from Highlight Therapeutics

A EARLY_PHASE1 clinical study on Advanced Hepatocellular Carcinoma and BCLC Stage B Hepatocellular Carcinoma, this trial is terminated or withdrawn. The trial is conducted by Highlight Therapeutics and has accumulated 10 data snapshots since 2021. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Apr 2021 – ~Jun 2021 · 2 months · monthly snapshotNot Yet Recruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Dec 2021 · 2 months · monthly snapshotNot Yet Recruiting~Dec 2021 – ~Jun 2022 · 6 months · monthly snapshotRecruiting~Jun 2022 – ~Jan 2023 · 7 months · monthly snapshotRecruiting~Jan 2023 – ~Apr 2023 · 3 months · monthly snapshotSuspended~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotTerminated~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotTerminated~Sep 2024 – present · 22 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2024 — Present [monthly]

    Terminated EARLY_PHASE1

  2. Jul 2024 — Sep 2024 [monthly]

    Terminated EARLY_PHASE1

  3. Apr 2023 — Jul 2024 [monthly]

    Terminated EARLY_PHASE1

    Status: SuspendedTerminated

  4. Jan 2023 — Apr 2023 [monthly]

    Suspended EARLY_PHASE1

    Status: RecruitingSuspended

  5. Jun 2022 — Jan 2023 [monthly]

    Recruiting EARLY_PHASE1

Show 5 earlier versions
  1. Dec 2021 — Jun 2022 [monthly]

    Recruiting EARLY_PHASE1

    Status: Not Yet RecruitingRecruiting

  2. Oct 2021 — Dec 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  3. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  4. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

  5. Apr 2021 — Jun 2021 [monthly]

    Not Yet Recruiting EARLY_PHASE1

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Highlight Therapeutics
  • Jonsson Comprehensive Cancer Center
  • Merck Sharp & Dohme LLC
Data source: Jonsson Comprehensive Cancer Center

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations