deltatrials
Terminated PHASE2 INTERVENTIONAL 1-arm NCT04780945

Functional Analysis of BRCAness (FAB)

Correlation Between Homologous Recombination Deficiency and Response to Olaparib in Patients With Recurrent Epithelial Ovarian Cancer (EOC)

Sponsor: Erasmus Medical Center

Updated 6 times since 2021 Last updated: Feb 12, 2026 Started: Jan 21, 2019 Primary completion: Dec 31, 2024 Completion: Dec 31, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

recruitment was lower than expected (28/55) due to registration of the IMP in the first and second line treatment

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A PHASE2 clinical study on BRCA1 Mutation and BRCA2 Mutation, this trial is terminated or withdrawn. The trial is conducted by Erasmus Medical Center and has accumulated 6 data snapshots since 2019. Oncology trials at this stage typically focus on safety, tolerability, and early efficacy signals.

Status Flow

~Apr 2021 – ~May 2021 · 30 days · monthly snapshotRecruiting~May 2021 – ~Jul 2023 · 26 months · monthly snapshotRecruiting~Jul 2023 – ~Jul 2024 · 12 months · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Feb 2026 · 17 months · monthly snapshotUnknown~Feb 2026 – present · 5 months · monthly snapshotTerminated

Change History

6 versions recorded
  1. Feb 2026 — Present [monthly]

    Terminated PHASE2

    Status: UnknownTerminated

  2. Sep 2024 — Feb 2026 [monthly]

    Unknown PHASE2

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2

    Status: Unknown StatusUnknown

  4. Jul 2023 — Jul 2024 [monthly]

    Unknown Status PHASE2

    Status: RecruitingUnknown Status

  5. May 2021 — Jul 2023 [monthly]

    Recruiting PHASE2

Show 1 earlier version
  1. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE2

    First recorded

Jan 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Erasmus Medical Center
  • Leiden University Medical Center
  • University Medical Center Groningen
Data source: Leiden University Medical Center

For direct contact, visit the study record on ClinicalTrials.gov .