deltatrials
Enrolling By Invitation PHASE3 INTERVENTIONAL 1-arm NCT04798430

Long-term Efficacy and Safety of OLE LIB003 in HoFH, HeFH, and High-risk CVD Patients Requiring Further LDL-C Reduction (LIBerate-OLE)

Open-Label Extension Phase 3 Study to Evaluate the Long-Term Efficacy and Safety of LIB003 in Patients With HoFH and HeFH, CVD, or at High Risk for CVD, on Stable Lipid-Lowering Therapy Requiring Additional LDL-C Reduction

Sponsor: LIB Therapeutics LLC

Interventions lerodalcibep
Updated 8 times since 2021 Last updated: Oct 21, 2024 Started: Dec 3, 2020 Primary completion: Jul 30, 2025 Completion: Dec 31, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04798430, this PHASE3 trial focuses on Cardiovascular Disease With Mention of Arteriosclerosis and Elevated Cholesterol and remains ongoing. Sponsored by LIB Therapeutics LLC, it has been updated 8 times since 2020, reflecting limited change activity. This study contributes longitudinal data to the cardiovascular research landscape.

Status Flow

~Apr 2021 – ~May 2021 · 30 days · monthly snapshotEnrolling By Invitation~May 2021 – ~Sep 2021 · 4 months · monthly snapshotEnrolling By Invitation~Sep 2021 – ~Apr 2023 · 19 months · monthly snapshotEnrolling By Invitation~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotEnrolling By Invitation~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotEnrolling By Invitation~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotEnrolling By Invitation~Nov 2024 – ~Sep 2025 · 10 months · monthly snapshotEnrolling By Invitation~Sep 2025 – present · 12 months · monthly snapshotEnrolling By Invitation

Change History

8 versions recorded
  1. Sep 2025 — Present [monthly]

    Enrolling By Invitation PHASE3

  2. Nov 2024 — Sep 2025 [monthly]

    Enrolling By Invitation PHASE3

  3. Sep 2024 — Nov 2024 [monthly]

    Enrolling By Invitation PHASE3

  4. Jul 2024 — Sep 2024 [monthly]

    Enrolling By Invitation PHASE3

  5. Apr 2023 — Jul 2024 [monthly]

    Enrolling By Invitation PHASE3

Show 3 earlier versions
  1. Sep 2021 — Apr 2023 [monthly]

    Enrolling By Invitation PHASE3

  2. May 2021 — Sep 2021 [monthly]

    Enrolling By Invitation PHASE3

  3. Apr 2021 — May 2021 [monthly]

    Enrolling By Invitation PHASE3

    First recorded

Dec 2020

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • LIB Therapeutics LLC
  • Medpace, Inc.
Data source: LIB Therapeutics LLC

For direct contact, visit the study record on ClinicalTrials.gov .