deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT04823130

Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis (DIFFEREN-STAD)

A Multi-center, Exploratory Study to Assess Dupilumab Effect on Pruritus Neuro-mechanisms in Patients With Atopic Dermatitis

Sponsor: Regeneron Pharmaceuticals

Updated 11 times since 2021 Last updated: Sep 15, 2025 Started: Apr 22, 2021 Primary completion: Jun 30, 2022 Completion: Aug 30, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE4 trial investigates Dermatitis Atopic and is currently completed. Regeneron Pharmaceuticals leads this study, which shows 11 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Apr 2021 – ~May 2021 · 30 days · monthly snapshotRecruiting~May 2021 – ~Jun 2021 · 31 days · monthly snapshotRecruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotRecruiting~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotRecruiting~Oct 2021 – ~Jun 2022 · 8 months · monthly snapshotRecruiting~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshotActive Not Recruiting~Sep 2022 – ~Aug 2023 · 11 months · monthly snapshotCompleted~Aug 2023 – ~Jul 2024 · 11 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Oct 2025 · 13 months · monthly snapshotCompleted~Oct 2025 – present · 9 months · monthly snapshotCompleted

Change History

11 versions recorded
  1. Oct 2025 — Present [monthly]

    Completed PHASE4

  2. Sep 2024 — Oct 2025 [monthly]

    Completed PHASE4

  3. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE4

  4. Aug 2023 — Jul 2024 [monthly]

    Completed PHASE4

  5. Sep 2022 — Aug 2023 [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

Show 6 earlier versions
  1. Jun 2022 — Sep 2022 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  2. Oct 2021 — Jun 2022 [monthly]

    Recruiting PHASE4

  3. Sep 2021 — Oct 2021 [monthly]

    Recruiting PHASE4

  4. Jun 2021 — Sep 2021 [monthly]

    Recruiting PHASE4

  5. May 2021 — Jun 2021 [monthly]

    Recruiting PHASE4

  6. Apr 2021 — May 2021 [monthly]

    Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Regeneron Pharmaceuticals
  • Sanofi
Data source: Sanofi

For direct contact, visit the study record on ClinicalTrials.gov .