deltatrials
Completed PHASE1 INTERVENTIONAL 4-arm NCT04838405

A Study of CT-388 in Otherwise Healthy Overweight and Obese Adults and Patients With Type 2 Diabetes Mellitus

A Phase 1 Randomized, Double Blind, Placebo Controlled, Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CT-388 in Otherwise Healthy Overweight and Obese Adult Participants and in Obese Patients With Type 2 Diabetes Mellitus

Sponsor: Carmot Australia First Pty Ltd

Conditions Diabetes
Interventions CT-388 Placebo
Updated 8 times since 2021 Last updated: Oct 15, 2025 Started: Apr 29, 2021 Primary completion: Jun 18, 2024 Completion: Aug 2, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04838405, this PHASE1 trial focuses on Diabetes and remains completed. Sponsored by Carmot Australia First Pty Ltd, it has been updated 8 times since 2021, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2021 – ~Sep 2022 · 16 months · monthly snapshotRecruiting~Sep 2022 – ~Jul 2024 · 22 months · monthly snapshotRecruiting~Jul 2024 – ~Aug 2024 · 31 days · monthly snapshotRecruiting~Aug 2024 – ~Sep 2024 · 31 days · monthly snapshotUnknown~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotUnknown~Oct 2024 – ~Mar 2025 · 5 months · monthly snapshotCompleted~Mar 2025 – ~Nov 2025 · 8 months · monthly snapshotCompleted~Nov 2025 – present · 10 months · monthly snapshotCompleted

Change History

8 versions recorded
  1. Nov 2025 — Present [monthly]

    Completed PHASE1

  2. Mar 2025 — Nov 2025 [monthly]

    Completed PHASE1

  3. Oct 2024 — Mar 2025 [monthly]

    Completed PHASE1

    Status: UnknownCompleted

  4. Sep 2024 — Oct 2024 [monthly]

    Unknown PHASE1

  5. Aug 2024 — Sep 2024 [monthly]

    Unknown PHASE1

    Status: RecruitingUnknown

Show 3 earlier versions
  1. Jul 2024 — Aug 2024 [monthly]

    Recruiting PHASE1

  2. Sep 2022 — Jul 2024 [monthly]

    Recruiting PHASE1

  3. May 2021 — Sep 2022 [monthly]

    Recruiting PHASE1

    First recorded

Apr 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Carmot Australia First Pty Ltd
  • Carmot Therapeutics, Inc.
Data source: Carmot Therapeutics, Inc.

For direct contact, visit the study record on ClinicalTrials.gov .