deltatrials
Completed NA INTERVENTIONAL 1-arm NCT04843436

PRIMO Post-Market Clinical Follow Up Study (PRIMO)

Post-Market, Non-Randomized, Multicentre PMCF Study to Monitor the Safety and Performance of Symani System in Microsurgical Reconstructive Procedures in a Real Life Setting

Sponsor: MMI (Medical Microinstruments, Inc.)

Conditions Blood Vessels, Lymphatic Ducts and Nerves Free Flaps Open Surgery
Interventions Symani Surgical System
Updated 21 times since 2021 Last updated: Dec 30, 2025 Started: Apr 13, 2021 Primary completion: Feb 6, 2025 Completion: Jul 18, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04843436, this NA trial focuses on Blood Vessels, Lymphatic Ducts and Nerves and Free Flaps and remains completed. Sponsored by MMI (Medical Microinstruments, Inc.), it has been updated 21 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2021 – ~Sep 2021 · 4 months · monthly snapshot~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshot~Feb 2022 – ~Apr 2022 · 59 days · monthly snapshot~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Dec 2022 · 30 days · monthly snapshot~Dec 2022 – ~Mar 2023 · 3 months · monthly snapshot~Mar 2023 – ~Jun 2023 · 3 months · monthly snapshot~Jun 2023 – ~Sep 2023 · 3 months · monthly snapshot~Sep 2023 – ~Oct 2023 · 30 days · monthly snapshot~Oct 2023 – ~Jul 2024 · 9 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Jan 2025 · 4 months · monthly snapshot~Jan 2025 – ~Jul 2025 · 6 months · monthly snapshot~Jul 2025 – ~Aug 2025 · 31 days · monthly snapshot~Aug 2025 – ~Sep 2025 · 31 days · monthly snapshot~Sep 2025 – ~Oct 2025 · 30 days · monthly snapshot~Oct 2025 – ~Dec 2025 · 2 months · monthly snapshot~Dec 2025 – ~Feb 2026 · 2 months · monthly snapshot~Feb 2026 – present · 5 months · monthly snapshot

Change History

21 versions recorded

  1. Feb 2026 — Present [monthly]

    Completed NA

  2. Dec 2025 — Feb 2026 [monthly]

    Completed NA

    Status: Active Not Recruiting → Completed

  3. Oct 2025 — Dec 2025 [monthly]

    Active Not Recruiting NA

  4. Sep 2025 — Oct 2025 [monthly]

    Active Not Recruiting NA

  5. Aug 2025 — Sep 2025 [monthly]

    Active Not Recruiting NA

    Status: Recruiting → Active Not Recruiting

▶ Show 16 earlier versions

  1. Jul 2025 — Aug 2025 [monthly]

    Recruiting NA

  2. Jan 2025 — Jul 2025 [monthly]

    Recruiting NA

  3. Sep 2024 — Jan 2025 [monthly]

    Recruiting NA

  4. Jul 2024 — Sep 2024 [monthly]

    Recruiting NA

  5. Oct 2023 — Jul 2024 [monthly]

    Recruiting NA

  6. Sep 2023 — Oct 2023 [monthly]

    Recruiting NA

  7. Jun 2023 — Sep 2023 [monthly]

    Recruiting NA

  8. Mar 2023 — Jun 2023 [monthly]

    Recruiting NA

  9. Dec 2022 — Mar 2023 [monthly]

    Recruiting NA

  10. Nov 2022 — Dec 2022 [monthly]

    Recruiting NA

  11. Sep 2022 — Nov 2022 [monthly]

    Recruiting NA

  12. Jun 2022 — Sep 2022 [monthly]

    Recruiting NA

  13. Apr 2022 — Jun 2022 [monthly]

    Recruiting NA

  14. Feb 2022 — Apr 2022 [monthly]

    Recruiting NA

  15. Sep 2021 — Feb 2022 [monthly]

    Recruiting NA

    Status: Not Yet Recruiting → Recruiting

  16. May 2021 — Sep 2021 [monthly]

    Not Yet Recruiting NA

    First recorded

Apr 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • MMI (Medical Microinstruments, Inc.)
Data source: MMI (Medical Microinstruments, Inc.)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations