Completed NA INTERVENTIONAL 4-arm NCT04851002

Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants

Analysing the Effects of Advanced-platelet Rich Fibrin and Concentrated Growth Factor on Implant Osseointegration With Respect to the Levels of TNF-α, RANKL, and OPG in Peri-implant Crevicular Fluid: a Split-mouth Design Study

Sponsor: Muhammet Atilgan

Conditions Bone Loss, Alveolar Edentulous Jaw Resorption, Bone

Interventions Application of advanced platelet rich fibrin with dental implants Application of concentrated growth factor with dental implants Control side of advanced platelet rich fibrin study group Control side of concentrated growth factor study group

Updated 4 times since 2021 Last updated: Apr 14, 2021 Started: Oct 3, 2019 Primary completion: Dec 15, 2020 Completion: Mar 20, 2021

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04851002, this NA trial focuses on Bone Loss, Alveolar and Edentulous Jaw and remains completed. Sponsored by Muhammet Atilgan, it has been updated 4 times since 2019, reflecting limited change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

Change History

4 versions recorded

Sep 2025 — Present [monthly]

Completed NA
Sep 2024 — Sep 2025 [monthly]

Completed NA
Jul 2024 — Sep 2024 [monthly]

Completed NA
May 2021 — Jul 2024 [monthly]

Completed NA

First recorded

Oct 2019

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

Muhammet Atilgan
Mustafa Kemal University

Data source: Mustafa Kemal University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Hatay, Turkey (Türkiye)