deltatrials
Terminated PHASE2/PHASE3 INTERVENTIONAL 2-arm NCT04857359

Dipraglurant (ADX48621) for the Treatment of Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Phase 2b/3, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Safety and Efficacy of Dipraglurant (ADX48621) for the Treatment of Dyskinesia in Patients With Parkinson's Disease Receiving Levodopa-based Therapy

Sponsor: Addex Pharma S.A.

Updated 10 times since 2021 Last updated: Aug 1, 2025 Started: Aug 6, 2021 Primary completion: Jun 17, 2022 Completion: Aug 15, 2022
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Terminated prior to completing enrollment goals due to COVID-related difficulties in recruiting patients

Other terminated trials from Addex Pharma S.A.

More terminations from Addex Pharma S.A.

Listed as NCT04857359, this PHASE2/PHASE3 trial focuses on Dyskinesia, Drug-Induced and Dyskinesias and remains terminated or withdrawn. Sponsored by Addex Pharma S.A., it has been updated 10 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~May 2021 – ~Jun 2021 · 31 days · monthly snapshotNot Yet Recruiting~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshotNot Yet Recruiting~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshotRecruiting~Nov 2021 – ~Mar 2022 · 4 months · monthly snapshotRecruiting~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshotRecruiting~Jun 2022 – ~Jun 2024 · 24 months · monthly snapshotRecruiting~Jun 2024 – ~Jul 2024 · 30 days · monthly snapshotUnknown Status~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotUnknown~Sep 2024 – ~Sep 2025 · 12 months · monthly snapshotUnknown~Sep 2025 – present · 10 months · monthly snapshotTerminated

Change History

10 versions recorded
  1. Sep 2025 — Present [monthly]

    Terminated PHASE2/PHASE3

    Status: UnknownTerminated

  2. Sep 2024 — Sep 2025 [monthly]

    Unknown PHASE2/PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Unknown PHASE2/PHASE3

    Status: Unknown StatusUnknown · Phase: PHASE2_PHASE3PHASE2/PHASE3

  4. Jun 2024 — Jul 2024 [monthly]

    Unknown Status PHASE2_PHASE3

    Status: RecruitingUnknown Status

  5. Jun 2022 — Jun 2024 [monthly]

    Recruiting PHASE2_PHASE3

Show 5 earlier versions
  1. Mar 2022 — Jun 2022 [monthly]

    Recruiting PHASE2_PHASE3

  2. Nov 2021 — Mar 2022 [monthly]

    Recruiting PHASE2_PHASE3

  3. Sep 2021 — Nov 2021 [monthly]

    Recruiting PHASE2_PHASE3

    Status: Not Yet RecruitingRecruiting

  4. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

  5. May 2021 — Jun 2021 [monthly]

    Not Yet Recruiting PHASE2_PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Addex Pharma S.A.
Data source: Addex Pharma S.A.

For direct contact, visit the study record on ClinicalTrials.gov .