Recruiting NA INTERVENTIONAL 2-arm NCT04884802

The GUARDIAN Trial

Tight Perioperative Blood Pressure Management to Reduce Serious Cardiovascular, Renal, and Cognitive Complications: The GUARDIAN Trial

Sponsor: The University of Texas Health Science Center, Houston

Conditions Blood Pressure

Interventions Routine blood pressure management Tight blood pressure management

Updated 7 times since 2021 Last updated: Aug 23, 2025 Started: Jul 25, 2021 Primary completion: Dec 31, 2026 Completion: Apr 25, 2027

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A NA clinical study on Blood Pressure, this trial is actively recruiting participants. The trial is conducted by The University of Texas Health Science Center, Houston and has accumulated 7 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

7 versions recorded

Sep 2025 — Present [monthly]

Recruiting NA
Sep 2024 — Sep 2025 [monthly]

Recruiting NA
Jul 2024 — Sep 2024 [monthly]

Recruiting NA
Sep 2023 — Jul 2024 [monthly]

Recruiting NA
Sep 2022 — Sep 2023 [monthly]

Recruiting NA

▶ Show 2 earlier versions

Sep 2021 — Sep 2022 [monthly]

Recruiting NA
Jun 2021 — Sep 2021 [monthly]

Recruiting NA

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

The University of Texas Health Science Center, Houston

Data source: The University of Texas Health Science Center, Houston

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

Bakırköy, Turkey (Türkiye) , Beijing, China , Chengdu, China , Cleveland, United States , Hong Kong, China , Houston, United States , Konya, Turkey (Türkiye) , Larissa, Greece , Omaha, United States , Rome, Italy and 4 more locations