deltatrials
Recruiting PHASE1/PHASE2 INTERVENTIONAL 1-arm NCT04906460

Open-label Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy (FORWARD-53)

An Open-label Phase 1b/2 Study of WVE-N531 in Patients With Duchenne Muscular Dystrophy

Sponsor: Wave Life Sciences Ltd.

Interventions WVE-N531
Updated 13 times since 2021 Last updated: Dec 8, 2025 Started: Sep 28, 2021 Primary completion: Jun 27, 2026 Completion: Apr 24, 2027
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04906460, this PHASE1/PHASE2 trial focuses on Duchenne Muscular Dystrophy and remains actively recruiting participants. Sponsored by Wave Life Sciences Ltd., it has been updated 13 times since 2021, reflecting substantial change activity. This study adds to the evidence base for this therapeutic area through structured, versioned documentation.

Status Flow

~Jun 2021 – ~Sep 2021 · 3 months · monthly snapshot~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshot~Nov 2021 – ~Jun 2022 · 7 months · monthly snapshot~Jun 2022 – ~Sep 2022 · 3 months · monthly snapshot~Sep 2022 – ~Mar 2024 · 18 months · monthly snapshot~Mar 2024 – ~Jul 2024 · 4 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshot~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshot~Jun 2025 – ~Oct 2025 · 4 months · monthly snapshot~Oct 2025 – ~Nov 2025 · 31 days · monthly snapshot~Nov 2025 – ~Jan 2026 · 2 months · monthly snapshot~Jan 2026 – present · 6 months · monthly snapshot

Change History

13 versions recorded
  1. Jan 2026 — Present [monthly]

    Recruiting PHASE1/PHASE2

  2. Nov 2025 — Jan 2026 [monthly]

    Recruiting PHASE1/PHASE2

    Status: Active Not RecruitingRecruiting

  3. Oct 2025 — Nov 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  4. Jun 2025 — Oct 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  5. Mar 2025 — Jun 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

Show 8 earlier versions
  1. Sep 2024 — Mar 2025 [monthly]

    Active Not Recruiting PHASE1/PHASE2

  2. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  3. Mar 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE1_PHASE2

    Status: RecruitingActive Not Recruiting

  4. Sep 2022 — Mar 2024 [monthly]

    Recruiting PHASE1_PHASE2

  5. Jun 2022 — Sep 2022 [monthly]

    Recruiting PHASE1_PHASE2

  6. Nov 2021 — Jun 2022 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  7. Sep 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  8. Jun 2021 — Sep 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Wave Life Sciences Ltd.
Data source: Wave Life Sciences Ltd.

For direct contact, visit the study record on ClinicalTrials.gov .