deltatrials
Terminated PHASE1 INTERVENTIONAL 1-arm NCT04937166

A Study of Dual-SIgnaling Protein 107 (DSP107) for Patients With Hematological Malignancies

An Open-label Phase Ib Study of DSP107 for Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS)

Sponsor: Kahr Medical

Updated 11 times since 2021 Last updated: Nov 6, 2025 Started: Jan 13, 2022 Primary completion: Apr 23, 2025 Completion: Oct 24, 2025
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Terminated

Slow enrolment

This PHASE1 trial investigates Acute Myeloid Leukemia and Chronic Myelomonocytic Leukemia and is currently terminated or withdrawn. Kahr Medical leads this study, which shows 11 recorded versions since 2022 — indicating substantial longitudinal coverage. As an oncology study, it adds to the longitudinal record of treatment development for this indication.

Status Flow

~Sep 2021 – ~Oct 2021 · 30 days · monthly snapshotNot Yet Recruiting~Oct 2021 – ~Jan 2022 · 3 months · monthly snapshotNot Yet Recruiting~Jan 2022 – ~Mar 2022 · 59 days · monthly snapshotNot Yet Recruiting~Mar 2022 – ~Dec 2022 · 9 months · monthly snapshotRecruiting~Dec 2022 – ~Apr 2023 · 4 months · monthly snapshotRecruiting~Apr 2023 – ~Jul 2024 · 15 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Nov 2024 · 2 months · monthly snapshotRecruiting~Nov 2024 – ~Jun 2025 · 7 months · monthly snapshotRecruiting~Jun 2025 – ~Dec 2025 · 6 months · monthly snapshotActive Not Recruiting~Dec 2025 – present · 7 months · monthly snapshotTerminated

Change History

11 versions recorded
  1. Dec 2025 — Present [monthly]

    Terminated PHASE1

    Status: Active Not RecruitingTerminated

  2. Jun 2025 — Dec 2025 [monthly]

    Active Not Recruiting PHASE1

    Status: RecruitingActive Not Recruiting

  3. Nov 2024 — Jun 2025 [monthly]

    Recruiting PHASE1

  4. Sep 2024 — Nov 2024 [monthly]

    Recruiting PHASE1

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1

Show 6 earlier versions
  1. Apr 2023 — Jul 2024 [monthly]

    Recruiting PHASE1

  2. Dec 2022 — Apr 2023 [monthly]

    Recruiting PHASE1

  3. Mar 2022 — Dec 2022 [monthly]

    Recruiting PHASE1

    Status: Not Yet RecruitingRecruiting

  4. Jan 2022 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE1

  5. Oct 2021 — Jan 2022 [monthly]

    Not Yet Recruiting PHASE1

    Phase: PHASE1_PHASE2PHASE1

  6. Sep 2021 — Oct 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Kahr Medical
Data source: Kahr Medical

For direct contact, visit the study record on ClinicalTrials.gov .