deltatrials
Recruiting PHASE2 INTERVENTIONAL 1-arm NCT04974671

Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

Phase II Trial Of Stereotactic Body Radiation Therapy (SBRT) for Oligoprogression on Immune Checkpoint Inhibitors (ICI) in Metastatic Renal Cell Carcinoma

Sponsor: Yale University

Conditions Metastatic Renal Cell Carcinoma Oligoprogressive Progression Renal Cell Carcinoma
Interventions Stereotactic Body Radiation Therapy
Updated 14 times since 2021 Last updated: Dec 3, 2025 Started: Dec 22, 2023 Primary completion: Jan 1, 2027 Completion: Apr 1, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04974671, this PHASE2 trial focuses on Metastatic Renal Cell Carcinoma and Oligoprogressive and remains actively recruiting participants. Sponsored by Yale University, it has been updated 14 times since 2023, reflecting substantial change activity. This study contributes to the evolving evidence base for cancer treatment protocols.

Status Flow

~Sep 2021 – ~Dec 2021 · 3 months · monthly snapshot~Dec 2021 – ~Mar 2022 · 3 months · monthly snapshot~Mar 2022 – ~Jun 2022 · 3 months · monthly snapshot~Jun 2022 – ~Jul 2022 · 30 days · monthly snapshot~Jul 2022 – ~Sep 2022 · 2 months · monthly snapshot~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Jan 2023 · 2 months · monthly snapshot~Jan 2023 – ~Dec 2023 · 11 months · monthly snapshot~Dec 2023 – ~Jul 2024 · 7 months · monthly snapshot~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshot~Oct 2024 – ~May 2025 · 7 months · monthly snapshot~May 2025 – ~Jan 2026 · 8 months · monthly snapshot~Jan 2026 – present · 7 months · monthly snapshot

Change History

14 versions recorded

  1. Jan 2026 — Present [monthly]

    Recruiting PHASE2

  2. May 2025 — Jan 2026 [monthly]

    Recruiting PHASE2

  3. Oct 2024 — May 2025 [monthly]

    Recruiting PHASE2

  4. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE2

  5. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE2

▶ Show 9 earlier versions

  1. Dec 2023 — Jul 2024 [monthly]

    Recruiting PHASE2

  2. Jan 2023 — Dec 2023 [monthly]

    Recruiting PHASE2

    Status: Not Yet Recruiting → Recruiting

  3. Nov 2022 — Jan 2023 [monthly]

    Not Yet Recruiting PHASE2

  4. Sep 2022 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE2

  5. Jul 2022 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE2

  6. Jun 2022 — Jul 2022 [monthly]

    Not Yet Recruiting PHASE2

  7. Mar 2022 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE2

  8. Dec 2021 — Mar 2022 [monthly]

    Not Yet Recruiting PHASE2

  9. Sep 2021 — Dec 2021 [monthly]

    Not Yet Recruiting PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Yale University
Data source: Yale University

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations