deltatrials
Recruiting PHASE3 INTERVENTIONAL 2-arm NCT04975178

Efficacy, Safety and Immunogenicity Evaluation of MTBVAC in Newborns in Sub-Saharan Africa (MTBVACN3)

Randomised, Double-Blind, Controlled Phase 3 Trial to Evaluate the Efficacy, Safety and Immunogenicity of MTBVAC in Healthy HIV Unexposed (HU) and HIV Exposed Uninfected (HEU) Newborns in Tuberculosis-Endemic Regions of Sub-Saharan Africa

Sponsor: Biofabri, S.L

Conditions Tuberculosis
Interventions BCG MTBVAC
Updated 7 times since 2021 Last updated: Feb 6, 2025 Started: Oct 17, 2022 Primary completion: Feb 28, 2029 Completion: Feb 28, 2029
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

Listed as NCT04975178, this PHASE3 trial focuses on Tuberculosis and remains actively recruiting participants. Sponsored by Biofabri, S.L, it has been updated 7 times since 2022, reflecting limited change activity. This study is part of the global effort to build evidence for infectious disease interventions.

Status Flow

~Sep 2021 – ~Sep 2022 · 12 months · monthly snapshotNot Yet Recruiting~Sep 2022 – ~Nov 2022 · 2 months · monthly snapshot~Nov 2022 – ~Nov 2023 · 12 months · monthly snapshotRecruiting~Nov 2023 – ~Jul 2024 · 8 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshot~Sep 2024 – ~Mar 2025 · 6 months · monthly snapshotRecruiting~Mar 2025 – present · 16 months · monthly snapshotRecruiting

Change History

7 versions recorded
  1. Mar 2025 — Present [monthly]

    Recruiting PHASE3

  2. Sep 2024 — Mar 2025 [monthly]

    Recruiting PHASE3

  3. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE3

  4. Nov 2023 — Jul 2024 [monthly]

    Recruiting PHASE3

  5. Nov 2022 — Nov 2023 [monthly]

    Recruiting PHASE3

    Status: Not Yet RecruitingRecruiting

Show 2 earlier versions
  1. Sep 2022 — Nov 2022 [monthly]

    Not Yet Recruiting PHASE3

  2. Sep 2021 — Sep 2022 [monthly]

    Not Yet Recruiting PHASE3

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Biofabri, S.L
  • Biomedical Research Center EPLS
  • Institut Pasteur de Madagascar
  • TuBerculosis Vaccine Initiative
  • Universidad de Zaragoza
  • University of Cape Town
  • University of KwaZulu
  • University of Stellenbosch
  • Wits Health Consortium (Pty) Ltd
Data source: Biofabri, S.L

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations