deltatrials
Completed PHASE4 INTERVENTIONAL 2-arm NCT04982614

HPV Vaccination in HIV Infected and HIV Uninfected Adolescents in Eswatini

A Multi-site, Open-label Non-inferiority Trial to Assess Immunogenicity of Two Doses of the Nonavalent Human Papillomavirus (HPV) Vaccine Among Children, Adolescents and Young Adults (9-26 Years) Living With HIV vs Three Doses of Nonavalent HPV Vaccine Among HIV Uninfected Young Women (15-26 Years) in Eswatini

Sponsor: Columbia University

Interventions Gardasil ® 9
Updated 12 times since 2021 Last updated: Aug 19, 2025 Started: Apr 1, 2022 Primary completion: Dec 9, 2024 Completion: Dec 9, 2024
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A PHASE4 clinical study on HPV Infection and HPV Vaccine, this trial is completed. The trial is conducted by Columbia University and has accumulated 12 data snapshots since 2022. Infectious disease trials contribute critical data for public health response and treatment development.

Status Flow

~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshotNot Yet Recruiting~Nov 2021 – ~Apr 2022 · 5 months · monthly snapshotNot Yet Recruiting~Apr 2022 – ~Jun 2022 · 2 months · monthly snapshotNot Yet Recruiting~Jun 2022 – ~Jun 2023 · 12 months · monthly snapshotRecruiting~Jun 2023 – ~Oct 2023 · 4 months · monthly snapshotActive Not Recruiting~Oct 2023 – ~Mar 2024 · 5 months · monthly snapshotActive Not Recruiting~Mar 2024 – ~Apr 2024 · 31 days · monthly snapshotActive Not Recruiting~Apr 2024 – ~Jul 2024 · 3 months · monthly snapshotActive Not Recruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotActive Not Recruiting~Sep 2024 – ~Dec 2024 · 3 months · monthly snapshotActive Not Recruiting~Dec 2024 – ~Sep 2025 · 9 months · monthly snapshotCompleted~Sep 2025 – present · 11 months · monthly snapshotCompleted

Change History

12 versions recorded
  1. Sep 2025 — Present [monthly]

    Completed PHASE4

  2. Dec 2024 — Sep 2025 [monthly]

    Completed PHASE4

    Status: Active Not RecruitingCompleted

  3. Sep 2024 — Dec 2024 [monthly]

    Active Not Recruiting PHASE4

  4. Jul 2024 — Sep 2024 [monthly]

    Active Not Recruiting PHASE4

  5. Apr 2024 — Jul 2024 [monthly]

    Active Not Recruiting PHASE4

Show 7 earlier versions
  1. Mar 2024 — Apr 2024 [monthly]

    Active Not Recruiting PHASE4

  2. Oct 2023 — Mar 2024 [monthly]

    Active Not Recruiting PHASE4

  3. Jun 2023 — Oct 2023 [monthly]

    Active Not Recruiting PHASE4

    Status: RecruitingActive Not Recruiting

  4. Jun 2022 — Jun 2023 [monthly]

    Recruiting PHASE4

    Status: Not Yet RecruitingRecruiting

  5. Apr 2022 — Jun 2022 [monthly]

    Not Yet Recruiting PHASE4

  6. Nov 2021 — Apr 2022 [monthly]

    Not Yet Recruiting PHASE4

  7. Sep 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE4

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Columbia University
  • Jhpiego
  • Merck Sharp & Dohme LLC
Data source: Columbia University

For direct contact, visit the study record on ClinicalTrials.gov .