deltatrials
Active Not Recruiting PHASE1/PHASE2 INTERVENTIONAL 2-arm NCT05017545

Carfilzomib and Belatacept for Desensitization (ADAPT)

Measuring the Impact of Carfilzomib and Belatacept on Allogeneic Desensitization in Prospective Kidney Transplant Recipients (ITN089ST)

Sponsor: Bristol-Myers Squibb

Updated 12 times since 2021 Last updated: Feb 18, 2026 Started: Dec 28, 2021 Primary completion: Feb 28, 2027 Completion: Feb 28, 2028
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1/PHASE2 trial investigates Highly Sensitized Prospective Kidney Transplant Recipients and is currently ongoing. Bristol-Myers Squibb leads this study, which shows 12 recorded versions since 2021 — indicating substantial longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2021 – ~Nov 2021 · 2 months · monthly snapshotNot Yet Recruiting~Nov 2021 – ~Feb 2022 · 3 months · monthly snapshotNot Yet Recruiting~Feb 2022 – ~Feb 2023 · 12 months · monthly snapshotRecruiting~Feb 2023 – ~Mar 2023 · 28 days · monthly snapshotRecruiting~Mar 2023 – ~Feb 2024 · 11 months · monthly snapshotRecruiting~Feb 2024 – ~Jul 2024 · 5 months · monthly snapshotRecruiting~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotRecruiting~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotRecruiting~Oct 2024 – ~Mar 2025 · 5 months · monthly snapshotRecruiting~Mar 2025 – ~Jun 2025 · 3 months · monthly snapshotRecruiting~Jun 2025 – ~Feb 2026 · 8 months · monthly snapshotRecruiting~Feb 2026 – present · 5 months · monthly snapshotActive Not Recruiting

Change History

12 versions recorded
  1. Feb 2026 — Present [monthly]

    Active Not Recruiting PHASE1/PHASE2

    Status: RecruitingActive Not Recruiting

  2. Jun 2025 — Feb 2026 [monthly]

    Recruiting PHASE1/PHASE2

  3. Mar 2025 — Jun 2025 [monthly]

    Recruiting PHASE1/PHASE2

  4. Oct 2024 — Mar 2025 [monthly]

    Recruiting PHASE1/PHASE2

  5. Sep 2024 — Oct 2024 [monthly]

    Recruiting PHASE1/PHASE2

Show 7 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Recruiting PHASE1/PHASE2

    Phase: PHASE1_PHASE2PHASE1/PHASE2

  2. Feb 2024 — Jul 2024 [monthly]

    Recruiting PHASE1_PHASE2

  3. Mar 2023 — Feb 2024 [monthly]

    Recruiting PHASE1_PHASE2

  4. Feb 2023 — Mar 2023 [monthly]

    Recruiting PHASE1_PHASE2

  5. Feb 2022 — Feb 2023 [monthly]

    Recruiting PHASE1_PHASE2

    Status: Not Yet RecruitingRecruiting

  6. Nov 2021 — Feb 2022 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

  7. Sep 2021 — Nov 2021 [monthly]

    Not Yet Recruiting PHASE1_PHASE2

    First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • Bristol-Myers Squibb
  • Immune Tolerance Network (ITN)
  • National Institute of Allergy and Infectious Diseases (NIAID)
  • PPD Development, LP
  • Rho Federal Systems Division, Inc.
Data source: National Institute of Allergy and Infectious Diseases (NIAID)

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations