Completed EARLY_PHASE1 INTERVENTIONAL 4-arm NCT05019430

Cocaine and Zolmitriptan

Behavioral Effects of Drugs (Inpatient): 42 (Cocaine and Zolmitriptan)

Sponsor: National Institute on Drug Abuse (NIDA)

Interventions Cocaine Placebo oral capsule Zolmitriptan

Updated 13 times since 2021 Last updated: Jul 16, 2025 Started: Oct 15, 2021 Primary completion: Jan 9, 2025 Completion: Jan 9, 2025

This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

A EARLY_PHASE1 clinical study on Cocaine Use Disorder, this trial is completed. The trial is conducted by National Institute on Drug Abuse (NIDA) and has accumulated 13 data snapshots since 2021. Longitudinal tracking of this trial contributes to a broader understanding of treatment development timelines.

Status Flow

Change History

13 versions recorded

Sep 2025 — Present [monthly]

Completed EARLY_PHASE1
Mar 2025 — Sep 2025 [monthly]

Completed EARLY_PHASE1
Feb 2025 — Mar 2025 [monthly]

Completed EARLY_PHASE1

Status: Recruiting → Completed
Jan 2025 — Feb 2025 [monthly]

Recruiting EARLY_PHASE1
Sep 2024 — Jan 2025 [monthly]

Recruiting EARLY_PHASE1

▶ Show 8 earlier versions

Jul 2024 — Sep 2024 [monthly]

Recruiting EARLY_PHASE1
Jan 2024 — Jul 2024 [monthly]

Recruiting EARLY_PHASE1
Jul 2023 — Jan 2024 [monthly]

Recruiting EARLY_PHASE1
Jan 2023 — Jul 2023 [monthly]

Recruiting EARLY_PHASE1
Jul 2022 — Jan 2023 [monthly]

Recruiting EARLY_PHASE1
Jan 2022 — Jul 2022 [monthly]

Recruiting EARLY_PHASE1
Nov 2021 — Jan 2022 [monthly]

Recruiting EARLY_PHASE1

Status: Not Yet Recruiting → Recruiting
Sep 2021 — Nov 2021 [monthly]

Not Yet Recruiting EARLY_PHASE1

First recorded

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:

National Institute on Drug Abuse (NIDA)
William Stoops

Data source: University of Kentucky

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations

• Lexington, United States