deltatrials
Completed PHASE1 INTERVENTIONAL 1-arm NCT05027568

A Study to Assess an ATX Inhibitor (IOA-289) in Healthy Volunteers

Randomized, Double-blind, Placebo-controlled, Dose Escalation Study for the Assessment of Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Single Ascending Oral Doses of IOA-289 in Healthy Male Volunteers

Sponsor: iOnctura

Conditions Healthy
Updated 9 times since 2021 Last updated: Mar 17, 2025 Started: Jun 28, 2021 Primary completion: Sep 7, 2021 Completion: Sep 7, 2021
This information is for research purposes only and is not medical advice. Consult a healthcare provider before making any medical decision.

This PHASE1 trial investigates Healthy and is currently completed. iOnctura leads this study, which shows 9 recorded versions since 2021 — indicating limited longitudinal coverage. The change history captured here reflects the iterative nature of clinical trial conduct.

Status Flow

~Sep 2021 – ~Feb 2022 · 5 months · monthly snapshotRecruiting~Feb 2022 – ~Nov 2022 · 9 months · monthly snapshotCompleted~Nov 2022 – ~Jul 2024 · 20 months · monthly snapshotCompleted~Jul 2024 – ~Sep 2024 · 2 months · monthly snapshotCompleted~Sep 2024 – ~Oct 2024 · 30 days · monthly snapshotCompleted~Oct 2024 – ~Dec 2024 · 2 months · monthly snapshotRecruiting~Dec 2024 – ~Jan 2025 · 31 days · monthly snapshotRecruiting~Jan 2025 – ~Apr 2025 · 3 months · monthly snapshotRecruiting~Apr 2025 – present · 15 months · monthly snapshotCompleted

Change History

9 versions recorded
  1. Apr 2025 — Present [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  2. Jan 2025 — Apr 2025 [monthly]

    Recruiting PHASE1

  3. Dec 2024 — Jan 2025 [monthly]

    Recruiting PHASE1

  4. Oct 2024 — Dec 2024 [monthly]

    Recruiting PHASE1

    Status: CompletedRecruiting

  5. Sep 2024 — Oct 2024 [monthly]

    Completed PHASE1

Show 4 earlier versions
  1. Jul 2024 — Sep 2024 [monthly]

    Completed PHASE1

  2. Nov 2022 — Jul 2024 [monthly]

    Completed PHASE1

  3. Feb 2022 — Nov 2022 [monthly]

    Completed PHASE1

    Status: RecruitingCompleted

  4. Sep 2021 — Feb 2022 [monthly]

    Recruiting PHASE1

    First recorded

Jun 2021

Trial started

Per CT.gov start date — pre-dates our first snapshot

Eligibility Summary

No eligibility information available.

Contact Information

Sponsor contact:
  • iOnctura
Data source: iOnctura

For direct contact, visit the study record on ClinicalTrials.gov .

Study Locations